A review of experimental models in colorectal carcinogenesis

Detalhes bibliográficos
Autor(a) principal: Machado,Vanessa Foresto
Data de Publicação: 2016
Outros Autores: Feitosa,Marley Ribeiro, Rocha,Jose Joaquim Ribeiro da, Féres,Omar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632016000100053
Resumo: ABSTRACT Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-carcinoma sequence similar to that found in humans. The objective of this manuscript is to review the most common chemical carcinogens used to induce experimental tumors and the usual methods of evaluation.
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spelling A review of experimental models in colorectal carcinogenesisAnimal modelsColorectal neoplasmsDiagnosisABSTRACT Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-carcinoma sequence similar to that found in humans. The objective of this manuscript is to review the most common chemical carcinogens used to induce experimental tumors and the usual methods of evaluation.Sociedade Brasileira de Coloproctologia2016-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632016000100053Journal of Coloproctology (Rio de Janeiro) v.36 n.1 2016reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2015.09.001info:eu-repo/semantics/openAccessMachado,Vanessa ForestoFeitosa,Marley RibeiroRocha,Jose Joaquim Ribeiro daFéres,Omareng2016-04-25T00:00:00Zoai:scielo:S2237-93632016000100053Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2016-04-25T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv A review of experimental models in colorectal carcinogenesis
title A review of experimental models in colorectal carcinogenesis
spellingShingle A review of experimental models in colorectal carcinogenesis
Machado,Vanessa Foresto
Animal models
Colorectal neoplasms
Diagnosis
title_short A review of experimental models in colorectal carcinogenesis
title_full A review of experimental models in colorectal carcinogenesis
title_fullStr A review of experimental models in colorectal carcinogenesis
title_full_unstemmed A review of experimental models in colorectal carcinogenesis
title_sort A review of experimental models in colorectal carcinogenesis
author Machado,Vanessa Foresto
author_facet Machado,Vanessa Foresto
Feitosa,Marley Ribeiro
Rocha,Jose Joaquim Ribeiro da
Féres,Omar
author_role author
author2 Feitosa,Marley Ribeiro
Rocha,Jose Joaquim Ribeiro da
Féres,Omar
author2_role author
author
author
dc.contributor.author.fl_str_mv Machado,Vanessa Foresto
Feitosa,Marley Ribeiro
Rocha,Jose Joaquim Ribeiro da
Féres,Omar
dc.subject.por.fl_str_mv Animal models
Colorectal neoplasms
Diagnosis
topic Animal models
Colorectal neoplasms
Diagnosis
description ABSTRACT Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-carcinoma sequence similar to that found in humans. The objective of this manuscript is to review the most common chemical carcinogens used to induce experimental tumors and the usual methods of evaluation.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632016000100053
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632016000100053
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2015.09.001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.36 n.1 2016
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
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reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
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