Experimental model of anal fistula in rats

Detalhes bibliográficos
Autor(a) principal: Arakaki,Mariana Sousa
Data de Publicação: 2013
Outros Autores: Santos,Carlos Henrique Marques dos, Falcão,Gustavo Ribeiro, Cassino,Pedro Carvalho, Nakamura,Ricardo Kenithi, Gomes,Nathália Favero, Santos,Ricardo Gasparin Coutinho dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632013000300135
Resumo: INTRODUCTION: the management of anal fistula remains debatable. The lack of a standard treatment free of complications stimulates the development of new options. OBJECTIVE: to develop an experimental model of anal fistula in rats. METHODS: to surgically create an anal fistula in 10 rats with Seton introduced through the anal sphincter musculature. The animals were euthanized for histological fistula tract assessment. RESULTS: all ten specimens histologically assessed had a lumen and surrounding granulation tissue. There was complete epithelialization of the tract in two samples, halfway epithelialization in one sample and epithelialization of only the outer portion in six samples. Epithelialization was not evident in one tract. CONCLUSION: anal fistulas in rats were histologically proved.
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spelling Experimental model of anal fistula in ratsFistulaAnal canalRats INTRODUCTION: the management of anal fistula remains debatable. The lack of a standard treatment free of complications stimulates the development of new options. OBJECTIVE: to develop an experimental model of anal fistula in rats. METHODS: to surgically create an anal fistula in 10 rats with Seton introduced through the anal sphincter musculature. The animals were euthanized for histological fistula tract assessment. RESULTS: all ten specimens histologically assessed had a lumen and surrounding granulation tissue. There was complete epithelialization of the tract in two samples, halfway epithelialization in one sample and epithelialization of only the outer portion in six samples. Epithelialization was not evident in one tract. CONCLUSION: anal fistulas in rats were histologically proved. Sociedade Brasileira de Coloproctologia2013-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632013000300135Journal of Coloproctology (Rio de Janeiro) v.33 n.3 2013reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2013.04.005info:eu-repo/semantics/openAccessArakaki,Mariana SousaSantos,Carlos Henrique Marques dosFalcão,Gustavo RibeiroCassino,Pedro CarvalhoNakamura,Ricardo KenithiGomes,Nathália FaveroSantos,Ricardo Gasparin Coutinho doseng2015-10-26T00:00:00Zoai:scielo:S2237-93632013000300135Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2015-10-26T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false
dc.title.none.fl_str_mv Experimental model of anal fistula in rats
title Experimental model of anal fistula in rats
spellingShingle Experimental model of anal fistula in rats
Arakaki,Mariana Sousa
Fistula
Anal canal
Rats
title_short Experimental model of anal fistula in rats
title_full Experimental model of anal fistula in rats
title_fullStr Experimental model of anal fistula in rats
title_full_unstemmed Experimental model of anal fistula in rats
title_sort Experimental model of anal fistula in rats
author Arakaki,Mariana Sousa
author_facet Arakaki,Mariana Sousa
Santos,Carlos Henrique Marques dos
Falcão,Gustavo Ribeiro
Cassino,Pedro Carvalho
Nakamura,Ricardo Kenithi
Gomes,Nathália Favero
Santos,Ricardo Gasparin Coutinho dos
author_role author
author2 Santos,Carlos Henrique Marques dos
Falcão,Gustavo Ribeiro
Cassino,Pedro Carvalho
Nakamura,Ricardo Kenithi
Gomes,Nathália Favero
Santos,Ricardo Gasparin Coutinho dos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Arakaki,Mariana Sousa
Santos,Carlos Henrique Marques dos
Falcão,Gustavo Ribeiro
Cassino,Pedro Carvalho
Nakamura,Ricardo Kenithi
Gomes,Nathália Favero
Santos,Ricardo Gasparin Coutinho dos
dc.subject.por.fl_str_mv Fistula
Anal canal
Rats
topic Fistula
Anal canal
Rats
description INTRODUCTION: the management of anal fistula remains debatable. The lack of a standard treatment free of complications stimulates the development of new options. OBJECTIVE: to develop an experimental model of anal fistula in rats. METHODS: to surgically create an anal fistula in 10 rats with Seton introduced through the anal sphincter musculature. The animals were euthanized for histological fistula tract assessment. RESULTS: all ten specimens histologically assessed had a lumen and surrounding granulation tissue. There was complete epithelialization of the tract in two samples, halfway epithelialization in one sample and epithelialization of only the outer portion in six samples. Epithelialization was not evident in one tract. CONCLUSION: anal fistulas in rats were histologically proved.
publishDate 2013
dc.date.none.fl_str_mv 2013-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632013000300135
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632013000300135
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jcol.2013.04.005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
publisher.none.fl_str_mv Sociedade Brasileira de Coloproctologia
dc.source.none.fl_str_mv Journal of Coloproctology (Rio de Janeiro) v.33 n.3 2013
reponame:Journal of Coloproctology (Rio de Janeiro. Online)
instname:Sociedade Brasileira de Coloproctologia (SBCP)
instacron:SBCP
instname_str Sociedade Brasileira de Coloproctologia (SBCP)
instacron_str SBCP
institution SBCP
reponame_str Journal of Coloproctology (Rio de Janeiro. Online)
collection Journal of Coloproctology (Rio de Janeiro. Online)
repository.name.fl_str_mv Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)
repository.mail.fl_str_mv ||sbcp@sbcp.org.br
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