A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of Coloproctology (Rio de Janeiro. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632015000100028 |
Resumo: | INTRODUCTION: Colorectal cancer is a disease influenced by genetic and environmental factors. Medicinal fungi and/or its extracts have been used in the adjuvant therapy of cancer because of their pharmacological, nutritional and immunomodulatory properties. OBJECTIVE: To evaluate the anthropometric profile of colorectal cancer women after dietary supplementation with Agaricus sylvaticus fungus. METHODS: Randomized, double-blind, placebo-controlled clinical trial was conducted in a public hospital in the Federal District - Brazil for six months. Sample of 32 patients with colorectal cancer, female, was separated into two groups: supplemented with Agaricus sylvaticus (30 mg/kg/day) and placebo. We conducted anthropometry (weight, height, body mass index, arm circumference, triceps skinfold, arm muscle circumference and fat percentage) during the treatment. The results were analyzed at three different times (before the start of treatment, three months and after six months supplementation) using the Microsoft Excel 2007 and SPSS 19.0, using Student's t-test and F, with significance for p ≤ 0.05. RESULTS: The Agaricus sylvaticus group showed a significant increase in body mass index, arm circumference, percent body fat and triceps skinfold, and non-significant increase in arm muscle circumference after six months of supplementation. These results were not observed in the placebo group. CONCLUSION: The results suggest that dietary supplementation with Agaricus sylvaticus is capable to have benefits in anthropometric parameters of women with colorectal cancer. |
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A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancerAnthropometryColorectal cancerAgaricus sylvaticus fungi INTRODUCTION: Colorectal cancer is a disease influenced by genetic and environmental factors. Medicinal fungi and/or its extracts have been used in the adjuvant therapy of cancer because of their pharmacological, nutritional and immunomodulatory properties. OBJECTIVE: To evaluate the anthropometric profile of colorectal cancer women after dietary supplementation with Agaricus sylvaticus fungus. METHODS: Randomized, double-blind, placebo-controlled clinical trial was conducted in a public hospital in the Federal District - Brazil for six months. Sample of 32 patients with colorectal cancer, female, was separated into two groups: supplemented with Agaricus sylvaticus (30 mg/kg/day) and placebo. We conducted anthropometry (weight, height, body mass index, arm circumference, triceps skinfold, arm muscle circumference and fat percentage) during the treatment. The results were analyzed at three different times (before the start of treatment, three months and after six months supplementation) using the Microsoft Excel 2007 and SPSS 19.0, using Student's t-test and F, with significance for p ≤ 0.05. RESULTS: The Agaricus sylvaticus group showed a significant increase in body mass index, arm circumference, percent body fat and triceps skinfold, and non-significant increase in arm muscle circumference after six months of supplementation. These results were not observed in the placebo group. CONCLUSION: The results suggest that dietary supplementation with Agaricus sylvaticus is capable to have benefits in anthropometric parameters of women with colorectal cancer. Sociedade Brasileira de Coloproctologia2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632015000100028Journal of Coloproctology (Rio de Janeiro) v.35 n.1 2015reponame:Journal of Coloproctology (Rio de Janeiro. Online)instname:Sociedade Brasileira de Coloproctologia (SBCP)instacron:SBCP10.1016/j.jcol.2015.01.001info:eu-repo/semantics/openAccessFortes,Renata CostaSouza,Jhuly AmadoNovaes,Maria Rita Carvalho Garbieng2015-08-04T00:00:00Zoai:scielo:S2237-93632015000100028Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-9363&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||sbcp@sbcp.org.br2317-64232237-9363opendoar:2015-08-04T00:00Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP)false |
dc.title.none.fl_str_mv |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
title |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
spellingShingle |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer Fortes,Renata Costa Anthropometry Colorectal cancer Agaricus sylvaticus fungi |
title_short |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
title_full |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
title_fullStr |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
title_full_unstemmed |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
title_sort |
A double-blind, randomized and placebo-controlled clinical trial with Agaricus sylvaticus fungus in anthropometric profile of women with colon cancer |
author |
Fortes,Renata Costa |
author_facet |
Fortes,Renata Costa Souza,Jhuly Amado Novaes,Maria Rita Carvalho Garbi |
author_role |
author |
author2 |
Souza,Jhuly Amado Novaes,Maria Rita Carvalho Garbi |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Fortes,Renata Costa Souza,Jhuly Amado Novaes,Maria Rita Carvalho Garbi |
dc.subject.por.fl_str_mv |
Anthropometry Colorectal cancer Agaricus sylvaticus fungi |
topic |
Anthropometry Colorectal cancer Agaricus sylvaticus fungi |
description |
INTRODUCTION: Colorectal cancer is a disease influenced by genetic and environmental factors. Medicinal fungi and/or its extracts have been used in the adjuvant therapy of cancer because of their pharmacological, nutritional and immunomodulatory properties. OBJECTIVE: To evaluate the anthropometric profile of colorectal cancer women after dietary supplementation with Agaricus sylvaticus fungus. METHODS: Randomized, double-blind, placebo-controlled clinical trial was conducted in a public hospital in the Federal District - Brazil for six months. Sample of 32 patients with colorectal cancer, female, was separated into two groups: supplemented with Agaricus sylvaticus (30 mg/kg/day) and placebo. We conducted anthropometry (weight, height, body mass index, arm circumference, triceps skinfold, arm muscle circumference and fat percentage) during the treatment. The results were analyzed at three different times (before the start of treatment, three months and after six months supplementation) using the Microsoft Excel 2007 and SPSS 19.0, using Student's t-test and F, with significance for p ≤ 0.05. RESULTS: The Agaricus sylvaticus group showed a significant increase in body mass index, arm circumference, percent body fat and triceps skinfold, and non-significant increase in arm muscle circumference after six months of supplementation. These results were not observed in the placebo group. CONCLUSION: The results suggest that dietary supplementation with Agaricus sylvaticus is capable to have benefits in anthropometric parameters of women with colorectal cancer. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632015000100028 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632015000100028 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jcol.2015.01.001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Coloproctologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Coloproctologia |
dc.source.none.fl_str_mv |
Journal of Coloproctology (Rio de Janeiro) v.35 n.1 2015 reponame:Journal of Coloproctology (Rio de Janeiro. Online) instname:Sociedade Brasileira de Coloproctologia (SBCP) instacron:SBCP |
instname_str |
Sociedade Brasileira de Coloproctologia (SBCP) |
instacron_str |
SBCP |
institution |
SBCP |
reponame_str |
Journal of Coloproctology (Rio de Janeiro. Online) |
collection |
Journal of Coloproctology (Rio de Janeiro. Online) |
repository.name.fl_str_mv |
Journal of Coloproctology (Rio de Janeiro. Online) - Sociedade Brasileira de Coloproctologia (SBCP) |
repository.mail.fl_str_mv |
||sbcp@sbcp.org.br |
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1752126477507231744 |