Is prevalence of colorectal polyps higher in patients with family history of colorectal cancer?

• Autor(a) principal: Murad-Regadas,Sthela Maria
• Data de Publicação: 2015
• Outros Autores: Bezerra,Carla Camila Rocha, Peixoto,Ana Ligia Rocha, Regadas,Francisco Sérgio Pinheiro, Rodrigues,Lusmar Veras, Siebra,José Airton Gonçalves, Fernandes,Graziela Olivia da Silva, Vasconcelos,Rafael Aragão
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of Coloproctology (Rio de Janeiro. Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632015000300146
• topic: Colonoscopy; Polyps; Prevention; Colorectal cancer

ABSTRACTObjectives:To assess the prevalence of polyps in patients with a family history of colorectal cancer, in comparison to asymptomatic individuals with indication for screening.Methods:A prospective study in a group of patients who underwent colonoscopy between 2012 and 2014. Patients were divided into two groups: Group I: no family history of colorectal cancer, and Group II: with a family history in first-degree relatives. Demographic characteristics, findings on colonoscopy, presence, location and histological type of polyps were evaluated, comparing the two groups.Results:214 patients were evaluated: 162 in Group I and 52 in Group II. The distribution of patients with polyps was similar in relation to gender: polyps were evidenced in Group I in 33 (20%) female patients vs. 10 (6%) male patients (p= 1.00); in Group II, the presence of polyps was evidenced in 9 (17%) female patients vs. 2 (4%) male patients (p= 1.00). Polypoid lesions were found in 54 patients (25%), with 43 (26%) in Group I and 11 (21%) in Group II. The prevalence of adenomas was similar in both groups (Group I = 18/37% vs. Group II = 10/50%) (p= 0.83).Conclusion:In this preliminary study, no correlation was found between prevalence of polyps and a family history of colorectal cancer.