Fixed drug eruption by etoricoxib confirmed by patch test

Detalhes bibliográficos
Autor(a) principal: Sousa,Aline Soares de
Data de Publicação: 2016
Outros Autores: Cardoso,José Carlos, Gouveia,Miguel Pinto, Gameiro,Ana Rita, Teixeira,Vera Barreto, Gonçalo,Maria
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000500652
Resumo: Abstract: Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.
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spelling Fixed drug eruption by etoricoxib confirmed by patch testDrug eruptionsHistologyPatch testsAbstract: Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.Sociedade Brasileira de Dermatologia2016-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000500652Anais Brasileiros de Dermatologia v.91 n.5 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164301info:eu-repo/semantics/openAccessSousa,Aline Soares deCardoso,José CarlosGouveia,Miguel PintoGameiro,Ana RitaTeixeira,Vera BarretoGonçalo,Mariaeng2016-11-04T00:00:00Zoai:scielo:S0365-05962016000500652Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-11-04T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Fixed drug eruption by etoricoxib confirmed by patch test
title Fixed drug eruption by etoricoxib confirmed by patch test
spellingShingle Fixed drug eruption by etoricoxib confirmed by patch test
Sousa,Aline Soares de
Drug eruptions
Histology
Patch tests
title_short Fixed drug eruption by etoricoxib confirmed by patch test
title_full Fixed drug eruption by etoricoxib confirmed by patch test
title_fullStr Fixed drug eruption by etoricoxib confirmed by patch test
title_full_unstemmed Fixed drug eruption by etoricoxib confirmed by patch test
title_sort Fixed drug eruption by etoricoxib confirmed by patch test
author Sousa,Aline Soares de
author_facet Sousa,Aline Soares de
Cardoso,José Carlos
Gouveia,Miguel Pinto
Gameiro,Ana Rita
Teixeira,Vera Barreto
Gonçalo,Maria
author_role author
author2 Cardoso,José Carlos
Gouveia,Miguel Pinto
Gameiro,Ana Rita
Teixeira,Vera Barreto
Gonçalo,Maria
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa,Aline Soares de
Cardoso,José Carlos
Gouveia,Miguel Pinto
Gameiro,Ana Rita
Teixeira,Vera Barreto
Gonçalo,Maria
dc.subject.por.fl_str_mv Drug eruptions
Histology
Patch tests
topic Drug eruptions
Histology
Patch tests
description Abstract: Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000500652
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000500652
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164301
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.5 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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