Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000400600 |
Resumo: | Linear IgA dermatosis has been increasingly associated with inflammatory bowel diseases, particularly ulcerative colitis. A 13-year-old male patient with an 11-month history of ulcerative colitis developed vesicles, pustules and erosions on the skin of the face, trunk and buttocks and in the oral mucosa. The work-up revealed a neutrophil-rich sub-epidermal bullous disease and linear deposition of IgA along the dermoepidermal junction, establishing the diagnosis of linear IgA dermatosis. The patient experienced unsatisfactory partial control of skin and intestinal symptoms despite the use of adalimumab, mesalazine, prednisone and dapsone for some months. After total colectomy, he presented complete remission of skin lesions, with no need of medications during two years of follow-up. A review of previously reported cases of the association is provided here and the role of ulcerative colitis in triggering linear IgA dermatosis is discussed. |
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Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomyColectomyCrohn's diseaseDapsoneImmunoglobulin AProctocolitisLinear IgA dermatosis has been increasingly associated with inflammatory bowel diseases, particularly ulcerative colitis. A 13-year-old male patient with an 11-month history of ulcerative colitis developed vesicles, pustules and erosions on the skin of the face, trunk and buttocks and in the oral mucosa. The work-up revealed a neutrophil-rich sub-epidermal bullous disease and linear deposition of IgA along the dermoepidermal junction, establishing the diagnosis of linear IgA dermatosis. The patient experienced unsatisfactory partial control of skin and intestinal symptoms despite the use of adalimumab, mesalazine, prednisone and dapsone for some months. After total colectomy, he presented complete remission of skin lesions, with no need of medications during two years of follow-up. A review of previously reported cases of the association is provided here and the role of ulcerative colitis in triggering linear IgA dermatosis is discussed.Sociedade Brasileira de Dermatologia2013-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000400600Anais Brasileiros de Dermatologia v.88 n.4 2013reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20131949info:eu-repo/semantics/openAccessVargas,Thiago Jeunon de SousaFialho,MônicaSantos,Luiza Tavares dosRodrigues,Palmira Assis de Jesus BarretoVargas,Ana Luisa Bittencourt Sampaio JeunonSousa,Maria Auxiliadora Jeunoneng2015-10-19T00:00:00Zoai:scielo:S0365-05962013000400600Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-10-19T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
title |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
spellingShingle |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy Vargas,Thiago Jeunon de Sousa Colectomy Crohn's disease Dapsone Immunoglobulin A Proctocolitis |
title_short |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
title_full |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
title_fullStr |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
title_full_unstemmed |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
title_sort |
Linear IgA dermatosis associated with ulcerative colitis: complete and sustained remission after total colectomy |
author |
Vargas,Thiago Jeunon de Sousa |
author_facet |
Vargas,Thiago Jeunon de Sousa Fialho,Mônica Santos,Luiza Tavares dos Rodrigues,Palmira Assis de Jesus Barreto Vargas,Ana Luisa Bittencourt Sampaio Jeunon Sousa,Maria Auxiliadora Jeunon |
author_role |
author |
author2 |
Fialho,Mônica Santos,Luiza Tavares dos Rodrigues,Palmira Assis de Jesus Barreto Vargas,Ana Luisa Bittencourt Sampaio Jeunon Sousa,Maria Auxiliadora Jeunon |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Vargas,Thiago Jeunon de Sousa Fialho,Mônica Santos,Luiza Tavares dos Rodrigues,Palmira Assis de Jesus Barreto Vargas,Ana Luisa Bittencourt Sampaio Jeunon Sousa,Maria Auxiliadora Jeunon |
dc.subject.por.fl_str_mv |
Colectomy Crohn's disease Dapsone Immunoglobulin A Proctocolitis |
topic |
Colectomy Crohn's disease Dapsone Immunoglobulin A Proctocolitis |
description |
Linear IgA dermatosis has been increasingly associated with inflammatory bowel diseases, particularly ulcerative colitis. A 13-year-old male patient with an 11-month history of ulcerative colitis developed vesicles, pustules and erosions on the skin of the face, trunk and buttocks and in the oral mucosa. The work-up revealed a neutrophil-rich sub-epidermal bullous disease and linear deposition of IgA along the dermoepidermal junction, establishing the diagnosis of linear IgA dermatosis. The patient experienced unsatisfactory partial control of skin and intestinal symptoms despite the use of adalimumab, mesalazine, prednisone and dapsone for some months. After total colectomy, he presented complete remission of skin lesions, with no need of medications during two years of follow-up. A review of previously reported cases of the association is provided here and the role of ulcerative colitis in triggering linear IgA dermatosis is discussed. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000400600 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000400600 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/abd1806-4841.20131949 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.88 n.4 2013 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126418725109760 |