Nephrogenic systemic fibrosis: concepts and perspectives
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400013 |
Resumo: | Nephrogenic systemic fibrosis is a chronic, progressive condition that develops in some patients with renal impairment after exposure to gadolinium-based contrast agents used in magnetic resonance imaging. Thickening of the skin is typical, usually affecting the extremities. Visceral organs can also be affected. The diagnosis of the disease requires careful clinicopathological correlation. Treatment aims at restoring renal function, which is associated with delayed progression and, eventually, remission of skin changes. Reduction and prevention of nephrogenic systemic fibrosis cases are based on limiting the use of gadolinium-based contrast agents in patients with kidney disorders (especially in patients with advanced renal failure at stages 4 and 5), and restricting their use to situations in which they are essential to diagnosis/follow-up. Other than limiting exposure to gadolinium based contrast agents, no effective preventive methods have been reported. Due to increased awareness about the disease among radiologists and nephrologists, the incidence of nephrogenic systemic fibrosis is declining. |
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Nephrogenic systemic fibrosis: concepts and perspectivesContrast mediaGadoliniumMagnetic resonance imagingNephrogenic fibrosing dermopathyRenal insufficiencyNephrogenic systemic fibrosis is a chronic, progressive condition that develops in some patients with renal impairment after exposure to gadolinium-based contrast agents used in magnetic resonance imaging. Thickening of the skin is typical, usually affecting the extremities. Visceral organs can also be affected. The diagnosis of the disease requires careful clinicopathological correlation. Treatment aims at restoring renal function, which is associated with delayed progression and, eventually, remission of skin changes. Reduction and prevention of nephrogenic systemic fibrosis cases are based on limiting the use of gadolinium-based contrast agents in patients with kidney disorders (especially in patients with advanced renal failure at stages 4 and 5), and restricting their use to situations in which they are essential to diagnosis/follow-up. Other than limiting exposure to gadolinium based contrast agents, no effective preventive methods have been reported. Due to increased awareness about the disease among radiologists and nephrologists, the incidence of nephrogenic systemic fibrosis is declining.Sociedade Brasileira de Dermatologia2012-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400013Anais Brasileiros de Dermatologia v.87 n.4 2012reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962012000400013info:eu-repo/semantics/openAccessIgreja,Ana Carolina de Souza MachadoMesquita,Kleyton de CarvalhoCowper,Shawn EdwinCosta,Izelda Maria Carvalhoeng2012-08-10T00:00:00Zoai:scielo:S0365-05962012000400013Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2012-08-10T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Nephrogenic systemic fibrosis: concepts and perspectives |
title |
Nephrogenic systemic fibrosis: concepts and perspectives |
spellingShingle |
Nephrogenic systemic fibrosis: concepts and perspectives Igreja,Ana Carolina de Souza Machado Contrast media Gadolinium Magnetic resonance imaging Nephrogenic fibrosing dermopathy Renal insufficiency |
title_short |
Nephrogenic systemic fibrosis: concepts and perspectives |
title_full |
Nephrogenic systemic fibrosis: concepts and perspectives |
title_fullStr |
Nephrogenic systemic fibrosis: concepts and perspectives |
title_full_unstemmed |
Nephrogenic systemic fibrosis: concepts and perspectives |
title_sort |
Nephrogenic systemic fibrosis: concepts and perspectives |
author |
Igreja,Ana Carolina de Souza Machado |
author_facet |
Igreja,Ana Carolina de Souza Machado Mesquita,Kleyton de Carvalho Cowper,Shawn Edwin Costa,Izelda Maria Carvalho |
author_role |
author |
author2 |
Mesquita,Kleyton de Carvalho Cowper,Shawn Edwin Costa,Izelda Maria Carvalho |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Igreja,Ana Carolina de Souza Machado Mesquita,Kleyton de Carvalho Cowper,Shawn Edwin Costa,Izelda Maria Carvalho |
dc.subject.por.fl_str_mv |
Contrast media Gadolinium Magnetic resonance imaging Nephrogenic fibrosing dermopathy Renal insufficiency |
topic |
Contrast media Gadolinium Magnetic resonance imaging Nephrogenic fibrosing dermopathy Renal insufficiency |
description |
Nephrogenic systemic fibrosis is a chronic, progressive condition that develops in some patients with renal impairment after exposure to gadolinium-based contrast agents used in magnetic resonance imaging. Thickening of the skin is typical, usually affecting the extremities. Visceral organs can also be affected. The diagnosis of the disease requires careful clinicopathological correlation. Treatment aims at restoring renal function, which is associated with delayed progression and, eventually, remission of skin changes. Reduction and prevention of nephrogenic systemic fibrosis cases are based on limiting the use of gadolinium-based contrast agents in patients with kidney disorders (especially in patients with advanced renal failure at stages 4 and 5), and restricting their use to situations in which they are essential to diagnosis/follow-up. Other than limiting exposure to gadolinium based contrast agents, no effective preventive methods have been reported. Due to increased awareness about the disease among radiologists and nephrologists, the incidence of nephrogenic systemic fibrosis is declining. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0365-05962012000400013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.87 n.4 2012 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126418254299136 |