Angiosarcoma in HIV-negative patients is not associated with HHV-8

Detalhes bibliográficos
Autor(a) principal: Avancini,João
Data de Publicação: 2016
Outros Autores: Sanches,José Antonio, Cherubim,Andre Pires Zanata, Pazzini,Renato, Oliveira,Cristina Mendes de, Sumita,Laura Masami, Valente,Neusa Yuriko Sakai, Pannuti,Claudio Sergio, Festa Neto,Cyro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600738
Resumo: Abstract: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
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spelling Angiosarcoma in HIV-negative patients is not associated with HHV-8HemangiosarcomaHerpesvirus 8, humanHIVAbstract: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.Sociedade Brasileira de Dermatologia2016-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600738Anais Brasileiros de Dermatologia v.91 n.6 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164730info:eu-repo/semantics/openAccessAvancini,JoãoSanches,José AntonioCherubim,Andre Pires ZanataPazzini,RenatoOliveira,Cristina Mendes deSumita,Laura MasamiValente,Neusa Yuriko SakaiPannuti,Claudio SergioFesta Neto,Cyroeng2017-01-06T00:00:00Zoai:scielo:S0365-05962016000600738Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-01-06T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Angiosarcoma in HIV-negative patients is not associated with HHV-8
title Angiosarcoma in HIV-negative patients is not associated with HHV-8
spellingShingle Angiosarcoma in HIV-negative patients is not associated with HHV-8
Avancini,João
Hemangiosarcoma
Herpesvirus 8, human
HIV
title_short Angiosarcoma in HIV-negative patients is not associated with HHV-8
title_full Angiosarcoma in HIV-negative patients is not associated with HHV-8
title_fullStr Angiosarcoma in HIV-negative patients is not associated with HHV-8
title_full_unstemmed Angiosarcoma in HIV-negative patients is not associated with HHV-8
title_sort Angiosarcoma in HIV-negative patients is not associated with HHV-8
author Avancini,João
author_facet Avancini,João
Sanches,José Antonio
Cherubim,Andre Pires Zanata
Pazzini,Renato
Oliveira,Cristina Mendes de
Sumita,Laura Masami
Valente,Neusa Yuriko Sakai
Pannuti,Claudio Sergio
Festa Neto,Cyro
author_role author
author2 Sanches,José Antonio
Cherubim,Andre Pires Zanata
Pazzini,Renato
Oliveira,Cristina Mendes de
Sumita,Laura Masami
Valente,Neusa Yuriko Sakai
Pannuti,Claudio Sergio
Festa Neto,Cyro
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Avancini,João
Sanches,José Antonio
Cherubim,Andre Pires Zanata
Pazzini,Renato
Oliveira,Cristina Mendes de
Sumita,Laura Masami
Valente,Neusa Yuriko Sakai
Pannuti,Claudio Sergio
Festa Neto,Cyro
dc.subject.por.fl_str_mv Hemangiosarcoma
Herpesvirus 8, human
HIV
topic Hemangiosarcoma
Herpesvirus 8, human
HIV
description Abstract: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600738
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600738
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164730
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.6 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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