Chromoblastomycosis caused by Rhinocladiella aquaspersa: first case report in Guatemala

• Autor(a) principal: Porras-López,Carlos
• Data de Publicação: 2019
• Outros Autores: Frías-De-León,María Guadalupe, Arenas,Roberto, Martínez-Herrera,Erick
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000500574
• topic: Chromoblastomycosis; Dermatology; Mycoses

Abstract The authors report a case of 40-year-old male patient with a five-year history of chromoblastomycosis on his right leg. Diagnosis was performed by direct 40% KOH exam of skin scales, culture with micro- and macromorphologic analysis, and genotypic characterization (sequencing of a fragment of the ITS region and phylogenetic analysis) of the isolated fungus. Rhinocladiella aquaspersa was identified as the etiological agent. Initially, the treatment was with oral itraconazole 200 mg/day for one year. However, the presence of “sclerotic cells” with filaments (“Borelli spiders”) resulted in a change of medical treatment: a higher dose of itraconazole (400 mg/day) and surgery, achieving clinical and mycological cure in one year. This is the first report of chromoblastomycosis caused by R. aquaspersa in Guatemala.