Detalhes bibliográficos
Autor(a) principal: |
Romiti,Ricardo |
Data de Publicação: |
2022 |
Outros Autores: |
Hirayama,André Luís da Silva,
Arnone,Marcelo,
Magalhães,Renata Ferreira |
Tipo de documento: |
Artigo
|
Idioma: |
eng |
Título da fonte: |
Anais brasileiros de dermatologia (Online) |
Texto Completo: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000100063
|
Resumo: |
Abstract Generalized pustular psoriasis (von Zumbusch) is a rare and acute eruption characterized by multiple sterile pustules over an erythematous and edematous background, eventually associated with psoriasis vulgaris. Classically, it manifests as a potentially severe systemic picture and demands prompt diagnosis and intervention. The duration of each flare-up and intervals between the pustular episodes is extremely variable. Recently, genetic abnormalities have been identified mainly in the familial and early variants of this disease. The therapeutic arsenal is limited; however, new drugs being evaluated aim to control both pustular flare-ups and disease recurrences. |