Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?

Detalhes bibliográficos
Autor(a) principal: Gaspar,Neide Kalil
Data de Publicação: 2016
Outros Autores: Aidé,Márcia Kalil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400479
Resumo: Abstract: Advances in knowledge of neurocellulars relations have provided new directions in the understanding and treatment of numerous conditions, including atopic dermatitis. It is known that emotional, physical, chemical or biological stimuli can generate more accentuated responses in atopic patients than in non-atopic individuals; however, the complex network of control covered by these influences, especially by neuropeptides and neurotrophins, and their genetic relations, still keep secrets to be revealed. Itching and airway hyperresponsiveness, the main aspects of atopy, are associated with disruption of the neurosensory network activity. Increased epidermal innervation and production of neurotrophins, neuropeptides, cytokines and proteases, in addition to their relations with the sensory receptors in an epidermis with poor lipid mantle, are the aspects currently covered for understanding atopic dermatitis.
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spelling Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?CytokinesDermatitis, atopicNeuropeptidesAbstract: Advances in knowledge of neurocellulars relations have provided new directions in the understanding and treatment of numerous conditions, including atopic dermatitis. It is known that emotional, physical, chemical or biological stimuli can generate more accentuated responses in atopic patients than in non-atopic individuals; however, the complex network of control covered by these influences, especially by neuropeptides and neurotrophins, and their genetic relations, still keep secrets to be revealed. Itching and airway hyperresponsiveness, the main aspects of atopy, are associated with disruption of the neurosensory network activity. Increased epidermal innervation and production of neurotrophins, neuropeptides, cytokines and proteases, in addition to their relations with the sensory receptors in an epidermis with poor lipid mantle, are the aspects currently covered for understanding atopic dermatitis.Sociedade Brasileira de Dermatologia2016-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400479Anais Brasileiros de Dermatologia v.91 n.4 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164211info:eu-repo/semantics/openAccessGaspar,Neide KalilAidé,Márcia Kalileng2016-08-26T00:00:00Zoai:scielo:S0365-05962016000400479Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-08-26T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
title Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
spellingShingle Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
Gaspar,Neide Kalil
Cytokines
Dermatitis, atopic
Neuropeptides
title_short Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
title_full Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
title_fullStr Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
title_full_unstemmed Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
title_sort Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
author Gaspar,Neide Kalil
author_facet Gaspar,Neide Kalil
Aidé,Márcia Kalil
author_role author
author2 Aidé,Márcia Kalil
author2_role author
dc.contributor.author.fl_str_mv Gaspar,Neide Kalil
Aidé,Márcia Kalil
dc.subject.por.fl_str_mv Cytokines
Dermatitis, atopic
Neuropeptides
topic Cytokines
Dermatitis, atopic
Neuropeptides
description Abstract: Advances in knowledge of neurocellulars relations have provided new directions in the understanding and treatment of numerous conditions, including atopic dermatitis. It is known that emotional, physical, chemical or biological stimuli can generate more accentuated responses in atopic patients than in non-atopic individuals; however, the complex network of control covered by these influences, especially by neuropeptides and neurotrophins, and their genetic relations, still keep secrets to be revealed. Itching and airway hyperresponsiveness, the main aspects of atopy, are associated with disruption of the neurosensory network activity. Increased epidermal innervation and production of neurotrophins, neuropeptides, cytokines and proteases, in addition to their relations with the sensory receptors in an epidermis with poor lipid mantle, are the aspects currently covered for understanding atopic dermatitis.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400479
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400479
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164211
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.4 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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