Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum

Detalhes bibliográficos
Autor(a) principal: Kavoussi,Hossein
Data de Publicação: 2016
Outros Autores: Ebrahimi,Ali, Rezaei,Mansour, Ramezani,Mazaher, Najafi,Behnaz, Kavoussi,Reza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400468
Resumo: Abstract: Background: Although many factors are involved in the etiology of xanthelasma palpebrum, lipid disorder is strongly associated with its induction. Xanthelasma palpebrum, the most common type of xanthoma, usually presents in middle-aged females and results in aesthetic problems. Objective: To evaluate thelipid profile and important clinical aspects of xanthelasma palpebrum patients. Methods: In this descriptive study, we enrolled 42xanthelasma palpebrumpatients, and 42 cases of non-inflammatory skin disorders as thecontrol group, matched for age and gender.The clinical characteristics of the patients and fasting serum lipid profile were recorded for both groups. The data obtained were analyzed using SPSS-16. Results: Xanthelasma palpebrum was found more commonly in middle-aged females with disease onset of less than 1 year, and without significant familial history of xanthoma. Furthermore,xanthelasma lesionswere most often seen in the upper lid with mild extension and was rarely associated with systemic disease. There was no statistically significant difference between two groups regarding hypertriglyceridemia (p= 0.231) and hypercholesterolemia (p= 0.302). The mean serum levels of cholesterol (221.51±60.4 mg/dl), triglyceride (185.98±71.1 mg/dl) and VLDL (37.7±17.6 mg/dl) were significantly higher and themedian HDL (36.2 (31, 41) mg/dl) level was lower in thepatient group. Conclusion: In our study, hypercholesterolemia and hypertriglyceridemia did not reveal a significant difference between thepatient and control groups; however, mean serum values for cholesterol, triglyceride, VLDL and HDL showed a significant difference between the two groups. Therefore, in addition to lipid abnormality, other factors could be involved in the pathogenesis of xanthelasma palpebrum.
id SBD-1_66a5045e5f978a4084d82afe14219838
oai_identifier_str oai:scielo:S0365-05962016000400468
network_acronym_str SBD-1
network_name_str Anais brasileiros de dermatologia (Online)
repository_id_str
spelling Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarumCholesterolCholesterol, HDLCholesterol, VLDLHypercholesterolemiaHyperlipidemiasHypertriglyceridemiaTriglyceridesXanthomatosisAbstract: Background: Although many factors are involved in the etiology of xanthelasma palpebrum, lipid disorder is strongly associated with its induction. Xanthelasma palpebrum, the most common type of xanthoma, usually presents in middle-aged females and results in aesthetic problems. Objective: To evaluate thelipid profile and important clinical aspects of xanthelasma palpebrum patients. Methods: In this descriptive study, we enrolled 42xanthelasma palpebrumpatients, and 42 cases of non-inflammatory skin disorders as thecontrol group, matched for age and gender.The clinical characteristics of the patients and fasting serum lipid profile were recorded for both groups. The data obtained were analyzed using SPSS-16. Results: Xanthelasma palpebrum was found more commonly in middle-aged females with disease onset of less than 1 year, and without significant familial history of xanthoma. Furthermore,xanthelasma lesionswere most often seen in the upper lid with mild extension and was rarely associated with systemic disease. There was no statistically significant difference between two groups regarding hypertriglyceridemia (p= 0.231) and hypercholesterolemia (p= 0.302). The mean serum levels of cholesterol (221.51±60.4 mg/dl), triglyceride (185.98±71.1 mg/dl) and VLDL (37.7±17.6 mg/dl) were significantly higher and themedian HDL (36.2 (31, 41) mg/dl) level was lower in thepatient group. Conclusion: In our study, hypercholesterolemia and hypertriglyceridemia did not reveal a significant difference between thepatient and control groups; however, mean serum values for cholesterol, triglyceride, VLDL and HDL showed a significant difference between the two groups. Therefore, in addition to lipid abnormality, other factors could be involved in the pathogenesis of xanthelasma palpebrum.Sociedade Brasileira de Dermatologia2016-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400468Anais Brasileiros de Dermatologia v.91 n.4 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164607info:eu-repo/semantics/openAccessKavoussi,HosseinEbrahimi,AliRezaei,MansourRamezani,MazaherNajafi,BehnazKavoussi,Rezaeng2016-08-26T00:00:00Zoai:scielo:S0365-05962016000400468Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-08-26T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
title Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
spellingShingle Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
Kavoussi,Hossein
Cholesterol
Cholesterol, HDL
Cholesterol, VLDL
Hypercholesterolemia
Hyperlipidemias
Hypertriglyceridemia
Triglycerides
Xanthomatosis
title_short Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
title_full Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
title_fullStr Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
title_full_unstemmed Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
title_sort Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
author Kavoussi,Hossein
author_facet Kavoussi,Hossein
Ebrahimi,Ali
Rezaei,Mansour
Ramezani,Mazaher
Najafi,Behnaz
Kavoussi,Reza
author_role author
author2 Ebrahimi,Ali
Rezaei,Mansour
Ramezani,Mazaher
Najafi,Behnaz
Kavoussi,Reza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Kavoussi,Hossein
Ebrahimi,Ali
Rezaei,Mansour
Ramezani,Mazaher
Najafi,Behnaz
Kavoussi,Reza
dc.subject.por.fl_str_mv Cholesterol
Cholesterol, HDL
Cholesterol, VLDL
Hypercholesterolemia
Hyperlipidemias
Hypertriglyceridemia
Triglycerides
Xanthomatosis
topic Cholesterol
Cholesterol, HDL
Cholesterol, VLDL
Hypercholesterolemia
Hyperlipidemias
Hypertriglyceridemia
Triglycerides
Xanthomatosis
description Abstract: Background: Although many factors are involved in the etiology of xanthelasma palpebrum, lipid disorder is strongly associated with its induction. Xanthelasma palpebrum, the most common type of xanthoma, usually presents in middle-aged females and results in aesthetic problems. Objective: To evaluate thelipid profile and important clinical aspects of xanthelasma palpebrum patients. Methods: In this descriptive study, we enrolled 42xanthelasma palpebrumpatients, and 42 cases of non-inflammatory skin disorders as thecontrol group, matched for age and gender.The clinical characteristics of the patients and fasting serum lipid profile were recorded for both groups. The data obtained were analyzed using SPSS-16. Results: Xanthelasma palpebrum was found more commonly in middle-aged females with disease onset of less than 1 year, and without significant familial history of xanthoma. Furthermore,xanthelasma lesionswere most often seen in the upper lid with mild extension and was rarely associated with systemic disease. There was no statistically significant difference between two groups regarding hypertriglyceridemia (p= 0.231) and hypercholesterolemia (p= 0.302). The mean serum levels of cholesterol (221.51±60.4 mg/dl), triglyceride (185.98±71.1 mg/dl) and VLDL (37.7±17.6 mg/dl) were significantly higher and themedian HDL (36.2 (31, 41) mg/dl) level was lower in thepatient group. Conclusion: In our study, hypercholesterolemia and hypertriglyceridemia did not reveal a significant difference between thepatient and control groups; however, mean serum values for cholesterol, triglyceride, VLDL and HDL showed a significant difference between the two groups. Therefore, in addition to lipid abnormality, other factors could be involved in the pathogenesis of xanthelasma palpebrum.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400468
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000400468
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164607
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.4 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
_version_ 1752126421094891520