Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site

Detalhes bibliográficos
Autor(a) principal: Wang,Fang
Data de Publicação: 2016
Outros Autores: Liu,Juan-Hua, Zhao,Yu-Kun, Luo,Di-Qing
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100076
Resumo: Abstract Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is extremely rare. We report a 19-year-old man with hepatitis B who had local leukocytoclastic vasculitis induced by interferon-gama injection at the injection site. After changing the injection sites and using the combined treatment of prednisone and colchicine, the previous lesion healed and no other cutaneous lesion occurred. We also made a mini review of such cases.
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spelling Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection siteCutaneousInjectionInterferon-gammaLeukocytoclasticSteroidVasculitisAbstract Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is extremely rare. We report a 19-year-old man with hepatitis B who had local leukocytoclastic vasculitis induced by interferon-gama injection at the injection site. After changing the injection sites and using the combined treatment of prednisone and colchicine, the previous lesion healed and no other cutaneous lesion occurred. We also made a mini review of such cases.Sociedade Brasileira de Dermatologia2016-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100076Anais Brasileiros de Dermatologia v.91 n.5 suppl.1 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164985info:eu-repo/semantics/openAccessWang,FangLiu,Juan-HuaZhao,Yu-KunLuo,Di-Qingeng2017-03-03T00:00:00Zoai:scielo:S0365-05962016001100076Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-03-03T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
title Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
spellingShingle Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
Wang,Fang
Cutaneous
Injection
Interferon-gamma
Leukocytoclastic
Steroid
Vasculitis
title_short Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
title_full Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
title_fullStr Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
title_full_unstemmed Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
title_sort Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
author Wang,Fang
author_facet Wang,Fang
Liu,Juan-Hua
Zhao,Yu-Kun
Luo,Di-Qing
author_role author
author2 Liu,Juan-Hua
Zhao,Yu-Kun
Luo,Di-Qing
author2_role author
author
author
dc.contributor.author.fl_str_mv Wang,Fang
Liu,Juan-Hua
Zhao,Yu-Kun
Luo,Di-Qing
dc.subject.por.fl_str_mv Cutaneous
Injection
Interferon-gamma
Leukocytoclastic
Steroid
Vasculitis
topic Cutaneous
Injection
Interferon-gamma
Leukocytoclastic
Steroid
Vasculitis
description Abstract Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is extremely rare. We report a 19-year-old man with hepatitis B who had local leukocytoclastic vasculitis induced by interferon-gama injection at the injection site. After changing the injection sites and using the combined treatment of prednisone and colchicine, the previous lesion healed and no other cutaneous lesion occurred. We also made a mini review of such cases.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100076
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016001100076
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164985
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.5 suppl.1 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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