Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700209 |
Resumo: | Abstract Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis. We present a rare case of multiple myeloma who immediately developed serious stomatitis and esophatitis associated with minor palmar-plantar erythrodysesthesia after a single course of pegylated liposomal doxorubicin. |
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Anais brasileiros de dermatologia (Online) |
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Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicinDoxorubicinEsophagitisStomatitisAbstract Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis. We present a rare case of multiple myeloma who immediately developed serious stomatitis and esophatitis associated with minor palmar-plantar erythrodysesthesia after a single course of pegylated liposomal doxorubicin.Sociedade Brasileira de Dermatologia2015-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700209Anais Brasileiros de Dermatologia v.90 n.3 suppl.1 2015reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20153708info:eu-repo/semantics/openAccessMa,HanChen,MeilanLiu,JunruLi,YingLi,Juaneng2015-11-19T00:00:00Zoai:scielo:S0365-05962015000700209Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-11-19T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
title |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
spellingShingle |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin Ma,Han Doxorubicin Esophagitis Stomatitis |
title_short |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
title_full |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
title_fullStr |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
title_full_unstemmed |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
title_sort |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin |
author |
Ma,Han |
author_facet |
Ma,Han Chen,Meilan Liu,Junru Li,Ying Li,Juan |
author_role |
author |
author2 |
Chen,Meilan Liu,Junru Li,Ying Li,Juan |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ma,Han Chen,Meilan Liu,Junru Li,Ying Li,Juan |
dc.subject.por.fl_str_mv |
Doxorubicin Esophagitis Stomatitis |
topic |
Doxorubicin Esophagitis Stomatitis |
description |
Abstract Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis. We present a rare case of multiple myeloma who immediately developed serious stomatitis and esophatitis associated with minor palmar-plantar erythrodysesthesia after a single course of pegylated liposomal doxorubicin. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700209 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700209 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/abd1806-4841.20153708 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.90 n.3 suppl.1 2015 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126420944945152 |