Diffuse cutaneous melanosis: rare complication of metastatic melanoma
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062 |
Resumo: | Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria. |
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Anais brasileiros de dermatologia (Online) |
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Diffuse cutaneous melanosis: rare complication of metastatic melanomaMelanosisMelanomaParaneoplastic syndromesAbstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria.Sociedade Brasileira de Dermatologia2017-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20176097info:eu-repo/semantics/openAccessAmaral,Ana Cristina Vervloet doDiniz,Lucia MartinsLucas,Elton AlmeidaCapeli,Rafaela Lorenzon de Aragãoeng2017-12-13T00:00:00Zoai:scielo:S0365-05962017001100062Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-12-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
title |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
spellingShingle |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma Amaral,Ana Cristina Vervloet do Melanosis Melanoma Paraneoplastic syndromes |
title_short |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
title_full |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
title_fullStr |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
title_full_unstemmed |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
title_sort |
Diffuse cutaneous melanosis: rare complication of metastatic melanoma |
author |
Amaral,Ana Cristina Vervloet do |
author_facet |
Amaral,Ana Cristina Vervloet do Diniz,Lucia Martins Lucas,Elton Almeida Capeli,Rafaela Lorenzon de Aragão |
author_role |
author |
author2 |
Diniz,Lucia Martins Lucas,Elton Almeida Capeli,Rafaela Lorenzon de Aragão |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Amaral,Ana Cristina Vervloet do Diniz,Lucia Martins Lucas,Elton Almeida Capeli,Rafaela Lorenzon de Aragão |
dc.subject.por.fl_str_mv |
Melanosis Melanoma Paraneoplastic syndromes |
topic |
Melanosis Melanoma Paraneoplastic syndromes |
description |
Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100062 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/abd1806-4841.20176097 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126422513614848 |