Cutaneous collagenous vasculopathy: light and transmission electron microscopy

Detalhes bibliográficos
Autor(a) principal: Sartori,Debora Sarzi
Data de Publicação: 2019
Outros Autores: Almeida Jr.,Hiram Larangeira de, Dorn,Timotio Volnei, Ruas,Caroline Pires
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000200211
Resumo: Abstract Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.
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spelling Cutaneous collagenous vasculopathy: light and transmission electron microscopyCollagen type IVMicroscopy, electron, transmissionSkin diseases, vascularVascular diseasesAbstract Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.Sociedade Brasileira de Dermatologia2019-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000200211Anais Brasileiros de Dermatologia v.94 n.2 2019reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20198166info:eu-repo/semantics/openAccessSartori,Debora SarziAlmeida Jr.,Hiram Larangeira deDorn,Timotio VolneiRuas,Caroline Pireseng2019-05-13T00:00:00Zoai:scielo:S0365-05962019000200211Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2019-05-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Cutaneous collagenous vasculopathy: light and transmission electron microscopy
title Cutaneous collagenous vasculopathy: light and transmission electron microscopy
spellingShingle Cutaneous collagenous vasculopathy: light and transmission electron microscopy
Sartori,Debora Sarzi
Collagen type IV
Microscopy, electron, transmission
Skin diseases, vascular
Vascular diseases
title_short Cutaneous collagenous vasculopathy: light and transmission electron microscopy
title_full Cutaneous collagenous vasculopathy: light and transmission electron microscopy
title_fullStr Cutaneous collagenous vasculopathy: light and transmission electron microscopy
title_full_unstemmed Cutaneous collagenous vasculopathy: light and transmission electron microscopy
title_sort Cutaneous collagenous vasculopathy: light and transmission electron microscopy
author Sartori,Debora Sarzi
author_facet Sartori,Debora Sarzi
Almeida Jr.,Hiram Larangeira de
Dorn,Timotio Volnei
Ruas,Caroline Pires
author_role author
author2 Almeida Jr.,Hiram Larangeira de
Dorn,Timotio Volnei
Ruas,Caroline Pires
author2_role author
author
author
dc.contributor.author.fl_str_mv Sartori,Debora Sarzi
Almeida Jr.,Hiram Larangeira de
Dorn,Timotio Volnei
Ruas,Caroline Pires
dc.subject.por.fl_str_mv Collagen type IV
Microscopy, electron, transmission
Skin diseases, vascular
Vascular diseases
topic Collagen type IV
Microscopy, electron, transmission
Skin diseases, vascular
Vascular diseases
description Abstract Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.
publishDate 2019
dc.date.none.fl_str_mv 2019-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000200211
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000200211
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20198166
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.94 n.2 2019
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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