Amantadine-induced livedo reticularis - Case report

• Autor(a) principal: Quaresma,Maria Victória
• Data de Publicação: 2015
• Outros Autores: Gomes,Ana Carolina Dias, Serruya,Aline, Vendramini,Dâmia Leal, Braga,Lara, Buçard,Alice Mota
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000500745
• topic: Amantadine; Livedo reticularis; Vascular diseases

AbstractLivedo reticularis is a spastic-anatomical condition of the small vessels which translates morphologically by a reticular pattern, interspersing cyanosis, pallor and erythema. The same can be congenital or acquired. Among the acquired, we highlight the physiological livedo reticularis and the idiopathic livedo by vasospasm; the latter configures the most common cause. The drug-induced type is less common. The drugs amantadine and norepinephrine are often implicated. Cyanosis is usually reversible if the causative factor is removed, however, with chronicity, the vessels may become permanently dilated and telangiectatic. We report a case of a patient diagnosed with Parkinson's disease with chronic livedo reticularis associated with the use of amantadine and improvement after discontinuation of the drug.