Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700162 |
Resumo: | Abstract We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of multiple subcutaneous nodules on her right leg. CT scan of the chest demonstrates pulmonary nodulosis. Skin biopsy was compatible with rheumatoid nodule. A diagnosis of "accelerated cutaneous and pulmonary nodulosis" was considered. Azathioprine was discontinued and Rituximab was restarted. Two months later, most of the subcutaneous nodules had disappeared. This is the second case report of accelerated rheumatoid nodulosis in association with Azathioprine treatment. |
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Anais brasileiros de dermatologia (Online) |
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Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritisArthritisrheumatoidAzathioprineRheumatoid noduleAbstract We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of multiple subcutaneous nodules on her right leg. CT scan of the chest demonstrates pulmonary nodulosis. Skin biopsy was compatible with rheumatoid nodule. A diagnosis of "accelerated cutaneous and pulmonary nodulosis" was considered. Azathioprine was discontinued and Rituximab was restarted. Two months later, most of the subcutaneous nodules had disappeared. This is the second case report of accelerated rheumatoid nodulosis in association with Azathioprine treatment.Sociedade Brasileira de Dermatologia2015-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700162Anais Brasileiros de Dermatologia v.90 n.3 suppl.1 2015reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20153750info:eu-repo/semantics/openAccessKellet,Cristian VeraNavarrete,Romina AndinoBombardieri,Sergio GonzálezManriquez,Juaneng2015-11-19T00:00:00Zoai:scielo:S0365-05962015000700162Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-11-19T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
title |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
spellingShingle |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis Kellet,Cristian Vera Arthritis rheumatoid Azathioprine Rheumatoid nodule |
title_short |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
title_full |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
title_fullStr |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
title_full_unstemmed |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
title_sort |
Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis |
author |
Kellet,Cristian Vera |
author_facet |
Kellet,Cristian Vera Navarrete,Romina Andino Bombardieri,Sergio González Manriquez,Juan |
author_role |
author |
author2 |
Navarrete,Romina Andino Bombardieri,Sergio González Manriquez,Juan |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Kellet,Cristian Vera Navarrete,Romina Andino Bombardieri,Sergio González Manriquez,Juan |
dc.subject.por.fl_str_mv |
Arthritis rheumatoid Azathioprine Rheumatoid nodule |
topic |
Arthritis rheumatoid Azathioprine Rheumatoid nodule |
description |
Abstract We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of multiple subcutaneous nodules on her right leg. CT scan of the chest demonstrates pulmonary nodulosis. Skin biopsy was compatible with rheumatoid nodule. A diagnosis of "accelerated cutaneous and pulmonary nodulosis" was considered. Azathioprine was discontinued and Rituximab was restarted. Two months later, most of the subcutaneous nodules had disappeared. This is the second case report of accelerated rheumatoid nodulosis in association with Azathioprine treatment. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700162 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700162 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/abd1806-4841.20153750 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.90 n.3 suppl.1 2015 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126420686995456 |