Lymphocytic thrombophilic arteritis with lower-limb ulcers

Detalhes bibliográficos
Autor(a) principal: Kim,Jessica Shen Tsy Wu
Data de Publicação: 2021
Outros Autores: Godofredo,Valeria Romero, Enokihara,Milvia Maria Simões e Silva, Vasconcellos,Mônica Ribeiro de Azevedo
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000300315
Resumo: Abstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson’s trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.
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spelling Lymphocytic thrombophilic arteritis with lower-limb ulcersArteritisSkin ulcerVasculitisAbstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson’s trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.Sociedade Brasileira de Dermatologia2021-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000300315Anais Brasileiros de Dermatologia v.96 n.3 2021reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2020.08.012info:eu-repo/semantics/openAccessKim,Jessica Shen Tsy WuGodofredo,Valeria RomeroEnokihara,Milvia Maria Simões e SilvaVasconcellos,Mônica Ribeiro de Azevedoeng2021-07-22T00:00:00Zoai:scielo:S0365-05962021000300315Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2021-07-22T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Lymphocytic thrombophilic arteritis with lower-limb ulcers
title Lymphocytic thrombophilic arteritis with lower-limb ulcers
spellingShingle Lymphocytic thrombophilic arteritis with lower-limb ulcers
Kim,Jessica Shen Tsy Wu
Arteritis
Skin ulcer
Vasculitis
title_short Lymphocytic thrombophilic arteritis with lower-limb ulcers
title_full Lymphocytic thrombophilic arteritis with lower-limb ulcers
title_fullStr Lymphocytic thrombophilic arteritis with lower-limb ulcers
title_full_unstemmed Lymphocytic thrombophilic arteritis with lower-limb ulcers
title_sort Lymphocytic thrombophilic arteritis with lower-limb ulcers
author Kim,Jessica Shen Tsy Wu
author_facet Kim,Jessica Shen Tsy Wu
Godofredo,Valeria Romero
Enokihara,Milvia Maria Simões e Silva
Vasconcellos,Mônica Ribeiro de Azevedo
author_role author
author2 Godofredo,Valeria Romero
Enokihara,Milvia Maria Simões e Silva
Vasconcellos,Mônica Ribeiro de Azevedo
author2_role author
author
author
dc.contributor.author.fl_str_mv Kim,Jessica Shen Tsy Wu
Godofredo,Valeria Romero
Enokihara,Milvia Maria Simões e Silva
Vasconcellos,Mônica Ribeiro de Azevedo
dc.subject.por.fl_str_mv Arteritis
Skin ulcer
Vasculitis
topic Arteritis
Skin ulcer
Vasculitis
description Abstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson’s trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000300315
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.abd.2020.08.012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.96 n.3 2021
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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