Pigmented Kamino bodies: a little-known histological finding. Prevalence in 19 cases of Reed nevus

• Autor(a) principal: Antunes,Ana Caroline Barreto
• Data de Publicação: 2017
• Outros Autores: Véspoli,Aline Caixeta Guimarães, Ferreira,Paula Silva, Valente,Neusa Yuriko Sakai
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300379
• topic: Histology; Nevus, spindle cell; Nevus, pigmented

Abstract The present study aimed to determine the prevalence of Kamino bodies in Reed nevus, since most studies to date show conflicting data on this issue. This was a retrospective observational study, in which the histopathology of 19 Reed nevus lesions were reviewed. The slides were stained by hematoxylin and eosin and periodic acid-Schiff, with a special focus placed on the identification of Kamino bodies. Some clinical data were also collected. The median patient age was 12 years (range of 2 to 58). The women to men ratio was 5:4. Lesions were located on different parts of the body. Kamino bodies were found in eleven lesions (57.89%). five showed pigmented Kamino bodies (26.31%), four non-pigmented Kamino bodies (21,05%), and 2 (10.52%) had both. Kamino bodies, pigmented or not, are a common histological finding in Reed nevus and may well represent a good marker to differentiate these from malignant melanomas.