Trichosporon isolation from human ungueal infections: is there a pathogenic role?

Detalhes bibliográficos
Autor(a) principal: Magalhães,Alba Regina de
Data de Publicação: 2016
Outros Autores: Nishikawa,Marília Martins, Mondino,Silvia Suzana Bona de, Macedo,Heloisa Werneck de, Rocha,Elisabeth Martins da Silva da, Baptista,Andrea Regina de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200173
Resumo: Abstract BACKGROUND: Although dermatophytes are considered the major cause of onychomycosis, many reports have incriminated non-dermatophyte moulds and yeasts in the disease’s etiology. Successive Trichosporon isolation from onychomycosis has led to the genus being suspected as a nail primary pathogen. OBJECTIVE: To determine the prevalence of Trichosporon isolation in onychomycosis patients who attended a mycology diagnostic service in Rio de Janeiro, Brazil, between January 2003 and December 2006. The study also includes a worldwide review on Trichosporon isolation prevalence in ungueal disease, emphasizing T. ovoides. METHODS: This retrospective study was conducted with the support of staff from the Mycology Laboratory at the Dermatological Service of Rio de Janeiro’s Santa Casa da Misericórdia (MLDS). RESULTS: Mycological analysis provided positive results equaling 47/5036 (0.93%) for Trichosporon spp.; obtained mainly as a single agent (72.35%), and from mixed cultures (27.65%; X2= 6.397; p= 0.018). The great majority belongs to the T. ovoides species (91.5%; n=43), obtained as a single isolate (74.41%; n= 32/43; X2 = 7.023; p= 0.014). CONCLUSIONS: Although T. ovoides is classically associated as an etiologic agent of white piedra, this study highlights its potential as a human nail disease pathogen. Our study opens doors for future epidemiologic and virulence factors aimed at determining whether T. ovoides is an important causative agent of onychomycosis in Brazil.
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spelling Trichosporon isolation from human ungueal infections: is there a pathogenic role?DiagnosisNail diseasesTrichosporonTrichosporonosisAbstract BACKGROUND: Although dermatophytes are considered the major cause of onychomycosis, many reports have incriminated non-dermatophyte moulds and yeasts in the disease’s etiology. Successive Trichosporon isolation from onychomycosis has led to the genus being suspected as a nail primary pathogen. OBJECTIVE: To determine the prevalence of Trichosporon isolation in onychomycosis patients who attended a mycology diagnostic service in Rio de Janeiro, Brazil, between January 2003 and December 2006. The study also includes a worldwide review on Trichosporon isolation prevalence in ungueal disease, emphasizing T. ovoides. METHODS: This retrospective study was conducted with the support of staff from the Mycology Laboratory at the Dermatological Service of Rio de Janeiro’s Santa Casa da Misericórdia (MLDS). RESULTS: Mycological analysis provided positive results equaling 47/5036 (0.93%) for Trichosporon spp.; obtained mainly as a single agent (72.35%), and from mixed cultures (27.65%; X2= 6.397; p= 0.018). The great majority belongs to the T. ovoides species (91.5%; n=43), obtained as a single isolate (74.41%; n= 32/43; X2 = 7.023; p= 0.014). CONCLUSIONS: Although T. ovoides is classically associated as an etiologic agent of white piedra, this study highlights its potential as a human nail disease pathogen. Our study opens doors for future epidemiologic and virulence factors aimed at determining whether T. ovoides is an important causative agent of onychomycosis in Brazil.Sociedade Brasileira de Dermatologia2016-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200173Anais Brasileiros de Dermatologia v.91 n.2 2016reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20164632info:eu-repo/semantics/openAccessMagalhães,Alba Regina deNishikawa,Marília MartinsMondino,Silvia Suzana Bona deMacedo,Heloisa Werneck deRocha,Elisabeth Martins da Silva daBaptista,Andrea Regina de Souzaeng2016-05-10T00:00:00Zoai:scielo:S0365-05962016000200173Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2016-05-10T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Trichosporon isolation from human ungueal infections: is there a pathogenic role?
title Trichosporon isolation from human ungueal infections: is there a pathogenic role?
spellingShingle Trichosporon isolation from human ungueal infections: is there a pathogenic role?
Magalhães,Alba Regina de
Diagnosis
Nail diseases
Trichosporon
Trichosporonosis
title_short Trichosporon isolation from human ungueal infections: is there a pathogenic role?
title_full Trichosporon isolation from human ungueal infections: is there a pathogenic role?
title_fullStr Trichosporon isolation from human ungueal infections: is there a pathogenic role?
title_full_unstemmed Trichosporon isolation from human ungueal infections: is there a pathogenic role?
title_sort Trichosporon isolation from human ungueal infections: is there a pathogenic role?
author Magalhães,Alba Regina de
author_facet Magalhães,Alba Regina de
Nishikawa,Marília Martins
Mondino,Silvia Suzana Bona de
Macedo,Heloisa Werneck de
Rocha,Elisabeth Martins da Silva da
Baptista,Andrea Regina de Souza
author_role author
author2 Nishikawa,Marília Martins
Mondino,Silvia Suzana Bona de
Macedo,Heloisa Werneck de
Rocha,Elisabeth Martins da Silva da
Baptista,Andrea Regina de Souza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Magalhães,Alba Regina de
Nishikawa,Marília Martins
Mondino,Silvia Suzana Bona de
Macedo,Heloisa Werneck de
Rocha,Elisabeth Martins da Silva da
Baptista,Andrea Regina de Souza
dc.subject.por.fl_str_mv Diagnosis
Nail diseases
Trichosporon
Trichosporonosis
topic Diagnosis
Nail diseases
Trichosporon
Trichosporonosis
description Abstract BACKGROUND: Although dermatophytes are considered the major cause of onychomycosis, many reports have incriminated non-dermatophyte moulds and yeasts in the disease’s etiology. Successive Trichosporon isolation from onychomycosis has led to the genus being suspected as a nail primary pathogen. OBJECTIVE: To determine the prevalence of Trichosporon isolation in onychomycosis patients who attended a mycology diagnostic service in Rio de Janeiro, Brazil, between January 2003 and December 2006. The study also includes a worldwide review on Trichosporon isolation prevalence in ungueal disease, emphasizing T. ovoides. METHODS: This retrospective study was conducted with the support of staff from the Mycology Laboratory at the Dermatological Service of Rio de Janeiro’s Santa Casa da Misericórdia (MLDS). RESULTS: Mycological analysis provided positive results equaling 47/5036 (0.93%) for Trichosporon spp.; obtained mainly as a single agent (72.35%), and from mixed cultures (27.65%; X2= 6.397; p= 0.018). The great majority belongs to the T. ovoides species (91.5%; n=43), obtained as a single isolate (74.41%; n= 32/43; X2 = 7.023; p= 0.014). CONCLUSIONS: Although T. ovoides is classically associated as an etiologic agent of white piedra, this study highlights its potential as a human nail disease pathogen. Our study opens doors for future epidemiologic and virulence factors aimed at determining whether T. ovoides is an important causative agent of onychomycosis in Brazil.
publishDate 2016
dc.date.none.fl_str_mv 2016-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200173
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200173
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20164632
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.91 n.2 2016
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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