Congenital and neonatal lupus erythematosus: two case reports

• Autor(a) principal: Frey,Marcos Noronha
• Data de Publicação: 2012
• Outros Autores: Ioppi,Ana Elisa Empinotti, Garbin,Gabriela Czarnobay, Furian,Roque Domingos, Bau,Ana Elisa Kiszewski
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000400019
• topic: Congenital, hereditary, and neonatal diseases and abnormalities; Infant, newborn; Lupus erythematosus, cutaneous

Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin within the first weeks or months of life. Congenital lupus erythematosus is a congenital variant of neonatal lupus erythematosus. We present one case of congenital lupus erythematosus and one case of neonatal lupus erythematous, showing the variability of this disease.