Azathioprine: its uses in dermatology,
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000600731 |
Resumo: | Abstract This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label indication for other dermatologic diseases. Its mechanism of action is described thoroughly, as well as precautions for monitoring adequate levels in patients using it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology it can be used in bullous and autoimmune diseases, and in other conditions, including intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe it safely to all patients who require it. |
id |
SBD-1_e3ce5b29b4a645edc44d49ff6076e249 |
---|---|
oai_identifier_str |
oai:scielo:S0365-05962020000600731 |
network_acronym_str |
SBD-1 |
network_name_str |
Anais brasileiros de dermatologia (Online) |
repository_id_str |
|
spelling |
Azathioprine: its uses in dermatology,AutoimmunityAzathioprinePemphigusAbstract This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label indication for other dermatologic diseases. Its mechanism of action is described thoroughly, as well as precautions for monitoring adequate levels in patients using it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology it can be used in bullous and autoimmune diseases, and in other conditions, including intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe it safely to all patients who require it.Sociedade Brasileira de Dermatologia2020-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000600731Anais Brasileiros de Dermatologia v.95 n.6 2020reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2020.05.003info:eu-repo/semantics/openAccessChavez-Alvarez,SoniaHerz-Ruelas,MairaVillarreal-Martinez,AlejandraOcampo-Candiani,JorgeGarza-Garza,RubicelaGomez-Flores,Minervaeng2020-11-30T00:00:00Zoai:scielo:S0365-05962020000600731Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2020-11-30T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Azathioprine: its uses in dermatology, |
title |
Azathioprine: its uses in dermatology, |
spellingShingle |
Azathioprine: its uses in dermatology, Chavez-Alvarez,Sonia Autoimmunity Azathioprine Pemphigus |
title_short |
Azathioprine: its uses in dermatology, |
title_full |
Azathioprine: its uses in dermatology, |
title_fullStr |
Azathioprine: its uses in dermatology, |
title_full_unstemmed |
Azathioprine: its uses in dermatology, |
title_sort |
Azathioprine: its uses in dermatology, |
author |
Chavez-Alvarez,Sonia |
author_facet |
Chavez-Alvarez,Sonia Herz-Ruelas,Maira Villarreal-Martinez,Alejandra Ocampo-Candiani,Jorge Garza-Garza,Rubicela Gomez-Flores,Minerva |
author_role |
author |
author2 |
Herz-Ruelas,Maira Villarreal-Martinez,Alejandra Ocampo-Candiani,Jorge Garza-Garza,Rubicela Gomez-Flores,Minerva |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Chavez-Alvarez,Sonia Herz-Ruelas,Maira Villarreal-Martinez,Alejandra Ocampo-Candiani,Jorge Garza-Garza,Rubicela Gomez-Flores,Minerva |
dc.subject.por.fl_str_mv |
Autoimmunity Azathioprine Pemphigus |
topic |
Autoimmunity Azathioprine Pemphigus |
description |
Abstract This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label indication for other dermatologic diseases. Its mechanism of action is described thoroughly, as well as precautions for monitoring adequate levels in patients using it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology it can be used in bullous and autoimmune diseases, and in other conditions, including intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe it safely to all patients who require it. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000600731 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000600731 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.abd.2020.05.003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.95 n.6 2020 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126424201822208 |