Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel

Detalhes bibliográficos
Autor(a) principal: Okada,Karin
Data de Publicação: 2017
Outros Autores: Nakamori,Rina, Mizutani,Hitoshi, Yamanaka,Keiichi
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100053
Resumo: Abstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cutaneous polyarteritis nodosa. The serum levels of inflammatory markers normalized with aspirin 100mg/day and prednisolone 10mg/day within 2 months, and there was no other skin or organ involvement over 18 months of follow up. However, serious refractory skin depressions and pigmentation remained after two years of treatment. This suggests the importance of early and aggressive therapy for cutaneous polyarteritis nodosa to prevent unsightly skin sequel, as well as control of disease activity.
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spelling Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequelPigmentationPolyarteritis nodosaVasculitisAbstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cutaneous polyarteritis nodosa. The serum levels of inflammatory markers normalized with aspirin 100mg/day and prednisolone 10mg/day within 2 months, and there was no other skin or organ involvement over 18 months of follow up. However, serious refractory skin depressions and pigmentation remained after two years of treatment. This suggests the importance of early and aggressive therapy for cutaneous polyarteritis nodosa to prevent unsightly skin sequel, as well as control of disease activity.Sociedade Brasileira de Dermatologia2017-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100053Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20175696info:eu-repo/semantics/openAccessOkada,KarinNakamori,RinaMizutani,HitoshiYamanaka,Keiichieng2017-12-13T00:00:00Zoai:scielo:S0365-05962017001100053Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-12-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
title Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
spellingShingle Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
Okada,Karin
Pigmentation
Polyarteritis nodosa
Vasculitis
title_short Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
title_full Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
title_fullStr Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
title_full_unstemmed Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
title_sort Cutaneous polyarteritis nodosa causing refractory skin deformation and pigmentation as sequel
author Okada,Karin
author_facet Okada,Karin
Nakamori,Rina
Mizutani,Hitoshi
Yamanaka,Keiichi
author_role author
author2 Nakamori,Rina
Mizutani,Hitoshi
Yamanaka,Keiichi
author2_role author
author
author
dc.contributor.author.fl_str_mv Okada,Karin
Nakamori,Rina
Mizutani,Hitoshi
Yamanaka,Keiichi
dc.subject.por.fl_str_mv Pigmentation
Polyarteritis nodosa
Vasculitis
topic Pigmentation
Polyarteritis nodosa
Vasculitis
description Abstract: A 39-year-old woman presented with prominent and painful livedo reticularis lesions spreading on her upper and lower extremities. Histopathologically, the small-to medium-sized arteries in the deep dermis and subcutis showed necrotizing vasculitis with cellular infiltration, suggesting cutaneous polyarteritis nodosa. The serum levels of inflammatory markers normalized with aspirin 100mg/day and prednisolone 10mg/day within 2 months, and there was no other skin or organ involvement over 18 months of follow up. However, serious refractory skin depressions and pigmentation remained after two years of treatment. This suggests the importance of early and aggressive therapy for cutaneous polyarteritis nodosa to prevent unsightly skin sequel, as well as control of disease activity.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100053
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20175696
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.92 n.5 suppl.1 2017
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
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reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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