Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation

Detalhes bibliográficos
Autor(a) principal: Duman,Hatice
Data de Publicação: 2017
Outros Autores: Topal,Ilteris Oguz, Kocaturk,Emek, Cure,Kubra, Mansuroglu,Ilknur
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300404
Resumo: Abstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis. A 42-year-old female presented with pustular lesions on the skin surface with erythema, facial edema, and occasional atypical target-like lesions after 21 days of treatment with 200mg/day hydroxychloroquine for rheumatoid arthritis, diagnosed one month previously. We report a case with acute generalized exanthematous pustulosis induced by hydroxychloroquine and treated with dapsone and systemic corticosteroid.
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spelling Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentationAcute generalized exanthematous pustulosisHydroxychloroquineErythema multiformeAbstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis. A 42-year-old female presented with pustular lesions on the skin surface with erythema, facial edema, and occasional atypical target-like lesions after 21 days of treatment with 200mg/day hydroxychloroquine for rheumatoid arthritis, diagnosed one month previously. We report a case with acute generalized exanthematous pustulosis induced by hydroxychloroquine and treated with dapsone and systemic corticosteroid.Sociedade Brasileira de Dermatologia2017-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300404Anais Brasileiros de Dermatologia v.92 n.3 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20175561info:eu-repo/semantics/openAccessDuman,HaticeTopal,Ilteris OguzKocaturk,EmekCure,KubraMansuroglu,Ilknureng2017-09-13T00:00:00Zoai:scielo:S0365-05962017000300404Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-09-13T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
title Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
spellingShingle Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
Duman,Hatice
Acute generalized exanthematous pustulosis
Hydroxychloroquine
Erythema multiforme
title_short Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
title_full Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
title_fullStr Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
title_full_unstemmed Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
title_sort Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
author Duman,Hatice
author_facet Duman,Hatice
Topal,Ilteris Oguz
Kocaturk,Emek
Cure,Kubra
Mansuroglu,Ilknur
author_role author
author2 Topal,Ilteris Oguz
Kocaturk,Emek
Cure,Kubra
Mansuroglu,Ilknur
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Duman,Hatice
Topal,Ilteris Oguz
Kocaturk,Emek
Cure,Kubra
Mansuroglu,Ilknur
dc.subject.por.fl_str_mv Acute generalized exanthematous pustulosis
Hydroxychloroquine
Erythema multiforme
topic Acute generalized exanthematous pustulosis
Hydroxychloroquine
Erythema multiforme
description Abstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis. A 42-year-old female presented with pustular lesions on the skin surface with erythema, facial edema, and occasional atypical target-like lesions after 21 days of treatment with 200mg/day hydroxychloroquine for rheumatoid arthritis, diagnosed one month previously. We report a case with acute generalized exanthematous pustulosis induced by hydroxychloroquine and treated with dapsone and systemic corticosteroid.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300404
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300404
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20175561
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.92 n.3 2017
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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