Rectal application of argan oil improves healing of colorectal anastomosis in rats
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000700565 |
Resumo: | Abstract Purpose: To investigate the possible effects of argan oil on the healing of colorectal anastomoses. Methods: I n Group 1 (sham), laparotomy was performed and the colon was mobilized. In the control (Group 2) and argan oil (Group 3) groups, colonic resection and anastomosis were applied. To the control and sham groups, 2 mL of 0.9% NaCl was administred rectally, and in the argan oil group, 2 mL/day argan oil was applied rectally for 7 days. Results: The mean bursting pressures of the argan oil and sham groups were significantly higher than the values in the control group. A significant difference was determined between the tissue hydroxyproline and prolidase levels of control group and other groups. Histopathologically, argan oil showed significant beneficial effects on colonic wound healing. In the argan oil and sham groups, the tissue malondialdehyde and fluorescent oxidation product levels were found to be lower and total sulfhydryl levels were higher than the control group. Conclusions: The rectally administered argan oil was observed to have significantly ameliorated wound healing parameters and exerted a significant antioxidant effect. This is the first study in the literature about the beneficial effects of argan oil on colorectal anastomoses. |
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Rectal application of argan oil improves healing of colorectal anastomosis in ratsAnastomosis, SurgicalAntioxidantsArganRatsAbstract Purpose: To investigate the possible effects of argan oil on the healing of colorectal anastomoses. Methods: I n Group 1 (sham), laparotomy was performed and the colon was mobilized. In the control (Group 2) and argan oil (Group 3) groups, colonic resection and anastomosis were applied. To the control and sham groups, 2 mL of 0.9% NaCl was administred rectally, and in the argan oil group, 2 mL/day argan oil was applied rectally for 7 days. Results: The mean bursting pressures of the argan oil and sham groups were significantly higher than the values in the control group. A significant difference was determined between the tissue hydroxyproline and prolidase levels of control group and other groups. Histopathologically, argan oil showed significant beneficial effects on colonic wound healing. In the argan oil and sham groups, the tissue malondialdehyde and fluorescent oxidation product levels were found to be lower and total sulfhydryl levels were higher than the control group. Conclusions: The rectally administered argan oil was observed to have significantly ameliorated wound healing parameters and exerted a significant antioxidant effect. This is the first study in the literature about the beneficial effects of argan oil on colorectal anastomoses.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2018-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000700565Acta Cirúrgica Brasileira v.33 n.7 2018reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020180070000002info:eu-repo/semantics/openAccessBarlas,Aziz MutluKuru,SerdarKismet,KemalCavusoglu,TurgutBag,Yusuf MuratSenes,MehmetCihan,NeslihanCelepli,PinarUnal,YilmazHucumenoglu,Semaeng2018-08-06T00:00:00Zoai:scielo:S0102-86502018000700565Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2018-08-06T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
title |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
spellingShingle |
Rectal application of argan oil improves healing of colorectal anastomosis in rats Barlas,Aziz Mutlu Anastomosis, Surgical Antioxidants Argan Rats |
title_short |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
title_full |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
title_fullStr |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
title_full_unstemmed |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
title_sort |
Rectal application of argan oil improves healing of colorectal anastomosis in rats |
author |
Barlas,Aziz Mutlu |
author_facet |
Barlas,Aziz Mutlu Kuru,Serdar Kismet,Kemal Cavusoglu,Turgut Bag,Yusuf Murat Senes,Mehmet Cihan,Neslihan Celepli,Pinar Unal,Yilmaz Hucumenoglu,Sema |
author_role |
author |
author2 |
Kuru,Serdar Kismet,Kemal Cavusoglu,Turgut Bag,Yusuf Murat Senes,Mehmet Cihan,Neslihan Celepli,Pinar Unal,Yilmaz Hucumenoglu,Sema |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Barlas,Aziz Mutlu Kuru,Serdar Kismet,Kemal Cavusoglu,Turgut Bag,Yusuf Murat Senes,Mehmet Cihan,Neslihan Celepli,Pinar Unal,Yilmaz Hucumenoglu,Sema |
dc.subject.por.fl_str_mv |
Anastomosis, Surgical Antioxidants Argan Rats |
topic |
Anastomosis, Surgical Antioxidants Argan Rats |
description |
Abstract Purpose: To investigate the possible effects of argan oil on the healing of colorectal anastomoses. Methods: I n Group 1 (sham), laparotomy was performed and the colon was mobilized. In the control (Group 2) and argan oil (Group 3) groups, colonic resection and anastomosis were applied. To the control and sham groups, 2 mL of 0.9% NaCl was administred rectally, and in the argan oil group, 2 mL/day argan oil was applied rectally for 7 days. Results: The mean bursting pressures of the argan oil and sham groups were significantly higher than the values in the control group. A significant difference was determined between the tissue hydroxyproline and prolidase levels of control group and other groups. Histopathologically, argan oil showed significant beneficial effects on colonic wound healing. In the argan oil and sham groups, the tissue malondialdehyde and fluorescent oxidation product levels were found to be lower and total sulfhydryl levels were higher than the control group. Conclusions: The rectally administered argan oil was observed to have significantly ameliorated wound healing parameters and exerted a significant antioxidant effect. This is the first study in the literature about the beneficial effects of argan oil on colorectal anastomoses. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000700565 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000700565 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s0102-865020180070000002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.33 n.7 2018 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126444924829696 |