Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury

Detalhes bibliográficos
Autor(a) principal: Feitosa,Matheus Levi Tajra
Data de Publicação: 2017
Outros Autores: Sarmento,Carlos Alberto Palmeira, Bocabello,Renato Zonzini, Beltrão-Braga,Patrícia Cristina Baleeiro, Pignatari,Graciela Conceição, Giglio,Robson Fortes, Miglino,Maria Angelica, Orlandin,Jéssica Rodrigues, Ambrósio,Carlos Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000700540
Resumo: Abstract Purpose: To investigate the therapeutic potential of human immature dental pulp stem cells in the treatment of chronic spinal cord injury in dogs. Methods: Three dogs of different breeds with chronic SCI were presented as animal clinical cases. Human immature dental pulp stem cells were injected at three points into the spinal cord, and the animals were evaluated by limb function and magnetic resonance imaging (MRI) pre and post-operative. Results: There was significant improvement from the limb function evaluated by Olby Scale, though it was not supported by the imaging data provided by MRI and clinical sign and evaluation. Conclusion: Human dental pulp stem cell therapy presents promising clinical results in dogs with chronic spinal cord injuries, if used in association with physical therapy.
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spelling Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injuryCell- and Tissue-Based TherapySpinal Cord InjuriesDental PulpDogsAbstract Purpose: To investigate the therapeutic potential of human immature dental pulp stem cells in the treatment of chronic spinal cord injury in dogs. Methods: Three dogs of different breeds with chronic SCI were presented as animal clinical cases. Human immature dental pulp stem cells were injected at three points into the spinal cord, and the animals were evaluated by limb function and magnetic resonance imaging (MRI) pre and post-operative. Results: There was significant improvement from the limb function evaluated by Olby Scale, though it was not supported by the imaging data provided by MRI and clinical sign and evaluation. Conclusion: Human dental pulp stem cell therapy presents promising clinical results in dogs with chronic spinal cord injuries, if used in association with physical therapy.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000700540Acta Cirúrgica Brasileira v.32 n.7 2017reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020170070000005info:eu-repo/semantics/openAccessFeitosa,Matheus Levi TajraSarmento,Carlos Alberto PalmeiraBocabello,Renato ZonziniBeltrão-Braga,Patrícia Cristina BaleeiroPignatari,Graciela ConceiçãoGiglio,Robson FortesMiglino,Maria AngelicaOrlandin,Jéssica RodriguesAmbrósio,Carlos Eduardoeng2017-08-02T00:00:00Zoai:scielo:S0102-86502017000700540Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2017-08-02T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
title Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
spellingShingle Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
Feitosa,Matheus Levi Tajra
Cell- and Tissue-Based Therapy
Spinal Cord Injuries
Dental Pulp
Dogs
title_short Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
title_full Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
title_fullStr Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
title_full_unstemmed Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
title_sort Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury
author Feitosa,Matheus Levi Tajra
author_facet Feitosa,Matheus Levi Tajra
Sarmento,Carlos Alberto Palmeira
Bocabello,Renato Zonzini
Beltrão-Braga,Patrícia Cristina Baleeiro
Pignatari,Graciela Conceição
Giglio,Robson Fortes
Miglino,Maria Angelica
Orlandin,Jéssica Rodrigues
Ambrósio,Carlos Eduardo
author_role author
author2 Sarmento,Carlos Alberto Palmeira
Bocabello,Renato Zonzini
Beltrão-Braga,Patrícia Cristina Baleeiro
Pignatari,Graciela Conceição
Giglio,Robson Fortes
Miglino,Maria Angelica
Orlandin,Jéssica Rodrigues
Ambrósio,Carlos Eduardo
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Feitosa,Matheus Levi Tajra
Sarmento,Carlos Alberto Palmeira
Bocabello,Renato Zonzini
Beltrão-Braga,Patrícia Cristina Baleeiro
Pignatari,Graciela Conceição
Giglio,Robson Fortes
Miglino,Maria Angelica
Orlandin,Jéssica Rodrigues
Ambrósio,Carlos Eduardo
dc.subject.por.fl_str_mv Cell- and Tissue-Based Therapy
Spinal Cord Injuries
Dental Pulp
Dogs
topic Cell- and Tissue-Based Therapy
Spinal Cord Injuries
Dental Pulp
Dogs
description Abstract Purpose: To investigate the therapeutic potential of human immature dental pulp stem cells in the treatment of chronic spinal cord injury in dogs. Methods: Three dogs of different breeds with chronic SCI were presented as animal clinical cases. Human immature dental pulp stem cells were injected at three points into the spinal cord, and the animals were evaluated by limb function and magnetic resonance imaging (MRI) pre and post-operative. Results: There was significant improvement from the limb function evaluated by Olby Scale, though it was not supported by the imaging data provided by MRI and clinical sign and evaluation. Conclusion: Human dental pulp stem cell therapy presents promising clinical results in dogs with chronic spinal cord injuries, if used in association with physical therapy.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000700540
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000700540
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s0102-865020170070000005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.32 n.7 2017
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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