Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005 |
Resumo: | PURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs. |
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Acta Cirúrgica Brasileira (Online) |
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Hemodynamics alterations during orthotopic liver experimental transplantation in pigsLiver TransplantationHemodynamic PhenomenaSwinePURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005Acta Cirúrgica Brasileira v.23 n.2 2008reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502008000200005info:eu-repo/semantics/openAccessTorres,Orlando Jorge MartinsPantoja,Patrícia BrandãoBarbosa,Erica SampaioBarros,Cristiany de AlmeidaServin,Elizabeth Teixeira NogueraServin,Santiago Cirilo Nogueraeng2008-03-26T00:00:00Zoai:scielo:S0102-86502008000200005Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2008-03-26T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
title |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
spellingShingle |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs Torres,Orlando Jorge Martins Liver Transplantation Hemodynamic Phenomena Swine |
title_short |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
title_full |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
title_fullStr |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
title_full_unstemmed |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
title_sort |
Hemodynamics alterations during orthotopic liver experimental transplantation in pigs |
author |
Torres,Orlando Jorge Martins |
author_facet |
Torres,Orlando Jorge Martins Pantoja,Patrícia Brandão Barbosa,Erica Sampaio Barros,Cristiany de Almeida Servin,Elizabeth Teixeira Noguera Servin,Santiago Cirilo Noguera |
author_role |
author |
author2 |
Pantoja,Patrícia Brandão Barbosa,Erica Sampaio Barros,Cristiany de Almeida Servin,Elizabeth Teixeira Noguera Servin,Santiago Cirilo Noguera |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Torres,Orlando Jorge Martins Pantoja,Patrícia Brandão Barbosa,Erica Sampaio Barros,Cristiany de Almeida Servin,Elizabeth Teixeira Noguera Servin,Santiago Cirilo Noguera |
dc.subject.por.fl_str_mv |
Liver Transplantation Hemodynamic Phenomena Swine |
topic |
Liver Transplantation Hemodynamic Phenomena Swine |
description |
PURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-86502008000200005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.23 n.2 2008 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126439081115648 |