Hemodynamics alterations during orthotopic liver experimental transplantation in pigs

Detalhes bibliográficos
Autor(a) principal: Torres,Orlando Jorge Martins
Data de Publicação: 2008
Outros Autores: Pantoja,Patrícia Brandão, Barbosa,Erica Sampaio, Barros,Cristiany de Almeida, Servin,Elizabeth Teixeira Noguera, Servin,Santiago Cirilo Noguera
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005
Resumo: PURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs.
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spelling Hemodynamics alterations during orthotopic liver experimental transplantation in pigsLiver TransplantationHemodynamic PhenomenaSwinePURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005Acta Cirúrgica Brasileira v.23 n.2 2008reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502008000200005info:eu-repo/semantics/openAccessTorres,Orlando Jorge MartinsPantoja,Patrícia BrandãoBarbosa,Erica SampaioBarros,Cristiany de AlmeidaServin,Elizabeth Teixeira NogueraServin,Santiago Cirilo Nogueraeng2008-03-26T00:00:00Zoai:scielo:S0102-86502008000200005Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2008-03-26T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
title Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
spellingShingle Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
Torres,Orlando Jorge Martins
Liver Transplantation
Hemodynamic Phenomena
Swine
title_short Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
title_full Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
title_fullStr Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
title_full_unstemmed Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
title_sort Hemodynamics alterations during orthotopic liver experimental transplantation in pigs
author Torres,Orlando Jorge Martins
author_facet Torres,Orlando Jorge Martins
Pantoja,Patrícia Brandão
Barbosa,Erica Sampaio
Barros,Cristiany de Almeida
Servin,Elizabeth Teixeira Noguera
Servin,Santiago Cirilo Noguera
author_role author
author2 Pantoja,Patrícia Brandão
Barbosa,Erica Sampaio
Barros,Cristiany de Almeida
Servin,Elizabeth Teixeira Noguera
Servin,Santiago Cirilo Noguera
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Torres,Orlando Jorge Martins
Pantoja,Patrícia Brandão
Barbosa,Erica Sampaio
Barros,Cristiany de Almeida
Servin,Elizabeth Teixeira Noguera
Servin,Santiago Cirilo Noguera
dc.subject.por.fl_str_mv Liver Transplantation
Hemodynamic Phenomena
Swine
topic Liver Transplantation
Hemodynamic Phenomena
Swine
description PURPOSE: To describe the hemodynamics alterations during orthotopic liver transplantation in pigs. METHODS: In the period from April 2004 to December 2005, forty-four female Landrace pigs, weighting between 32 and 38 Kg were undergone to orthotopic liver transplantation. The animals were divided into two groups, donor and recipient pairs, which received whole liver grafts. The surgical procedure was divided into four parts: harvested, back-table, hepatectomy of the recipient and implantation. We analyze heart rate, blood gas, mean systemic arterial pressure (MAP-mmHg), central venous pressure, pH, Na-, K+, Cl-, Ca+ and urinary output. RESULTS: The mean anhepatic time was 69 min, cold ischemia was 252.2 min and back-table was 56.6 min. Blood pressure and heart rate dropped significantly during anhepatic phase and after revascularization. Blood gas and electrolytes alterations were observed during anhepatic and reperfusion phases. Although alterations were noted during these phases, the hemodynamic status was recovered and stabilized in the end of the surgery. CONCLUSIONS: Simplified technique of liver transplant was achieved and description of hemodynamic alterations was possible in pigs.
publishDate 2008
dc.date.none.fl_str_mv 2008-04-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502008000200005
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502008000200005
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.23 n.2 2008
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
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instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
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reponame_str Acta Cirúrgica Brasileira (Online)
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repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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