Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen

Detalhes bibliográficos
Autor(a) principal: Costa,Fábio Wildson Gurgel
Data de Publicação: 2012
Outros Autores: Pessoa,Rosana Maria Andrade, Nogueira,Carlos Bruno Pinheiro, Pereira,Karuza Maria Alves, Brito,Gerly Anne de Castro, Soares,Eduardo Costa Studart
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000200014
Resumo: PURPOSE: To study the main effects of local use of liquid nitrogen on bone marrow tissue in rats. METHODS: The femoral diaphyses of 42 Wistar rats were exposed to three local and sequential applications of liquid nitrogen for one or two minutes, intercalated with periods of five minutes of passive thawing. The animals were sacrificed after one, two, four and 12 weeks and the specimens obtained were analyzed histomorphologically. RESULTS: In the second experimental week of one-minute protocol, histological degree of inflammation obtained a mean score of one (mild), ranging from 0 (absent or scarce) and two (moderate) (Kruskal-Wallis test p=0.01). In the second experimental week of two-minute protocol, degree of inflammation to the medullar tissue obtained an average score of two (Kruskal-Wallis test p=0.01). CONCLUSION: The degree of inflammation of the bone marrow tissue was higher in protocol of three applications of two minutes compared to protocol of three applications of one minute.
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spelling Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogenSurgery, OralNitrogenFemurRatsPURPOSE: To study the main effects of local use of liquid nitrogen on bone marrow tissue in rats. METHODS: The femoral diaphyses of 42 Wistar rats were exposed to three local and sequential applications of liquid nitrogen for one or two minutes, intercalated with periods of five minutes of passive thawing. The animals were sacrificed after one, two, four and 12 weeks and the specimens obtained were analyzed histomorphologically. RESULTS: In the second experimental week of one-minute protocol, histological degree of inflammation obtained a mean score of one (mild), ranging from 0 (absent or scarce) and two (moderate) (Kruskal-Wallis test p=0.01). In the second experimental week of two-minute protocol, degree of inflammation to the medullar tissue obtained an average score of two (Kruskal-Wallis test p=0.01). CONCLUSION: The degree of inflammation of the bone marrow tissue was higher in protocol of three applications of two minutes compared to protocol of three applications of one minute.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2012-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000200014Acta Cirúrgica Brasileira v.27 n.2 2012reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502012000200014info:eu-repo/semantics/openAccessCosta,Fábio Wildson GurgelPessoa,Rosana Maria AndradeNogueira,Carlos Bruno PinheiroPereira,Karuza Maria AlvesBrito,Gerly Anne de CastroSoares,Eduardo Costa Studarteng2012-02-27T00:00:00Zoai:scielo:S0102-86502012000200014Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2012-02-27T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
title Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
spellingShingle Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
Costa,Fábio Wildson Gurgel
Surgery, Oral
Nitrogen
Femur
Rats
title_short Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
title_full Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
title_fullStr Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
title_full_unstemmed Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
title_sort Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
author Costa,Fábio Wildson Gurgel
author_facet Costa,Fábio Wildson Gurgel
Pessoa,Rosana Maria Andrade
Nogueira,Carlos Bruno Pinheiro
Pereira,Karuza Maria Alves
Brito,Gerly Anne de Castro
Soares,Eduardo Costa Studart
author_role author
author2 Pessoa,Rosana Maria Andrade
Nogueira,Carlos Bruno Pinheiro
Pereira,Karuza Maria Alves
Brito,Gerly Anne de Castro
Soares,Eduardo Costa Studart
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Costa,Fábio Wildson Gurgel
Pessoa,Rosana Maria Andrade
Nogueira,Carlos Bruno Pinheiro
Pereira,Karuza Maria Alves
Brito,Gerly Anne de Castro
Soares,Eduardo Costa Studart
dc.subject.por.fl_str_mv Surgery, Oral
Nitrogen
Femur
Rats
topic Surgery, Oral
Nitrogen
Femur
Rats
description PURPOSE: To study the main effects of local use of liquid nitrogen on bone marrow tissue in rats. METHODS: The femoral diaphyses of 42 Wistar rats were exposed to three local and sequential applications of liquid nitrogen for one or two minutes, intercalated with periods of five minutes of passive thawing. The animals were sacrificed after one, two, four and 12 weeks and the specimens obtained were analyzed histomorphologically. RESULTS: In the second experimental week of one-minute protocol, histological degree of inflammation obtained a mean score of one (mild), ranging from 0 (absent or scarce) and two (moderate) (Kruskal-Wallis test p=0.01). In the second experimental week of two-minute protocol, degree of inflammation to the medullar tissue obtained an average score of two (Kruskal-Wallis test p=0.01). CONCLUSION: The degree of inflammation of the bone marrow tissue was higher in protocol of three applications of two minutes compared to protocol of three applications of one minute.
publishDate 2012
dc.date.none.fl_str_mv 2012-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000200014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000200014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502012000200014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.27 n.2 2012
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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