Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula

• Autor(a) principal: Oliveira,Douglas Guimaraes de
• Data de Publicação: 2015
• Outros Autores: Toneloto,Maria Gabriela Cavicchia, Moreira,Marcos Mello, Bustorff-Silva,Joaquim Murray, Souza,Gabriel Franco de, Martins,Luiz Claudio, Kosour,Carolina, Dragosavac,Desanka, Falcão,Antonio Luis Eiras
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Acta Cirúrgica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100001
• topic: Respiratory Tract Fistula; Respiration, Artificial; Models, Animal; Swine

PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure.