Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000300201 |
Resumo: | Abstract Purpose: To evaluate the healing potential of the electrospinning membranes of Poly (Lactic Acid) (PLA) associated with Sedum dendroideum extract in burn injuries in rats. Methods: Seventy-five rats were submitted to burn injury on their back skin: (C) untreated; (F) with daily topical application of S. dendroideum extract; (M) with electrospinning membranes of PLA; (MF10) with electrospinning membranes of PLA with 10% S. dendroideum extract; (MF25) with electrospinning membranes of PLA with 25% S. dendroideum extract. Tissue samples were taken after 2, 6 and 14 days of the burn injury and were subjected to histomorfometric analysis of quantification of fibroblasts, collagen fibers, blood vessels, and inflammatory infiltrate Results: The histomorphometric analysis showed an increase in the number of fibroblasts, collagen fibers and blood vessels in the burns treated with membranes of PLA, associated or not with the 10% and 25% extract. The extract of S. dendroideum promoted the increase of collagen fibers. Conclusion: The electrospinning PLA membrane, isolated or associated with the S. dendrodeum extract, favored the healing of burn injuries in this experimental model, with an increase of fibroblasts, collagen fibers, and blood vessels. S. dendroideum isolated only stimulated the collagenesis. |
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Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in ratsWound HealingBurnsPhytotherapySkinRatsAbstract Purpose: To evaluate the healing potential of the electrospinning membranes of Poly (Lactic Acid) (PLA) associated with Sedum dendroideum extract in burn injuries in rats. Methods: Seventy-five rats were submitted to burn injury on their back skin: (C) untreated; (F) with daily topical application of S. dendroideum extract; (M) with electrospinning membranes of PLA; (MF10) with electrospinning membranes of PLA with 10% S. dendroideum extract; (MF25) with electrospinning membranes of PLA with 25% S. dendroideum extract. Tissue samples were taken after 2, 6 and 14 days of the burn injury and were subjected to histomorfometric analysis of quantification of fibroblasts, collagen fibers, blood vessels, and inflammatory infiltrate Results: The histomorphometric analysis showed an increase in the number of fibroblasts, collagen fibers and blood vessels in the burns treated with membranes of PLA, associated or not with the 10% and 25% extract. The extract of S. dendroideum promoted the increase of collagen fibers. Conclusion: The electrospinning PLA membrane, isolated or associated with the S. dendrodeum extract, favored the healing of burn injuries in this experimental model, with an increase of fibroblasts, collagen fibers, and blood vessels. S. dendroideum isolated only stimulated the collagenesis.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000300201Acta Cirúrgica Brasileira v.35 n.3 2020reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020200030000002info:eu-repo/semantics/openAccessBinotto,Juliane PeliçariMendes,Larissa GiorgettiGaspi,Fernanda Oliveira de GaspariEsquisatto,Marcelo Augusto MarretoAndrade,Thiago Antonio Moretti deMendonça,Fernanda Aparecida SampaioSantos,Gláucia Maria Techeng2020-05-18T00:00:00Zoai:scielo:S0102-86502020000300201Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2020-05-18T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
title |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
spellingShingle |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats Binotto,Juliane Peliçari Wound Healing Burns Phytotherapy Skin Rats |
title_short |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
title_full |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
title_fullStr |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
title_full_unstemmed |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
title_sort |
Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats |
author |
Binotto,Juliane Peliçari |
author_facet |
Binotto,Juliane Peliçari Mendes,Larissa Giorgetti Gaspi,Fernanda Oliveira de Gaspari Esquisatto,Marcelo Augusto Marreto Andrade,Thiago Antonio Moretti de Mendonça,Fernanda Aparecida Sampaio Santos,Gláucia Maria Tech |
author_role |
author |
author2 |
Mendes,Larissa Giorgetti Gaspi,Fernanda Oliveira de Gaspari Esquisatto,Marcelo Augusto Marreto Andrade,Thiago Antonio Moretti de Mendonça,Fernanda Aparecida Sampaio Santos,Gláucia Maria Tech |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Binotto,Juliane Peliçari Mendes,Larissa Giorgetti Gaspi,Fernanda Oliveira de Gaspari Esquisatto,Marcelo Augusto Marreto Andrade,Thiago Antonio Moretti de Mendonça,Fernanda Aparecida Sampaio Santos,Gláucia Maria Tech |
dc.subject.por.fl_str_mv |
Wound Healing Burns Phytotherapy Skin Rats |
topic |
Wound Healing Burns Phytotherapy Skin Rats |
description |
Abstract Purpose: To evaluate the healing potential of the electrospinning membranes of Poly (Lactic Acid) (PLA) associated with Sedum dendroideum extract in burn injuries in rats. Methods: Seventy-five rats were submitted to burn injury on their back skin: (C) untreated; (F) with daily topical application of S. dendroideum extract; (M) with electrospinning membranes of PLA; (MF10) with electrospinning membranes of PLA with 10% S. dendroideum extract; (MF25) with electrospinning membranes of PLA with 25% S. dendroideum extract. Tissue samples were taken after 2, 6 and 14 days of the burn injury and were subjected to histomorfometric analysis of quantification of fibroblasts, collagen fibers, blood vessels, and inflammatory infiltrate Results: The histomorphometric analysis showed an increase in the number of fibroblasts, collagen fibers and blood vessels in the burns treated with membranes of PLA, associated or not with the 10% and 25% extract. The extract of S. dendroideum promoted the increase of collagen fibers. Conclusion: The electrospinning PLA membrane, isolated or associated with the S. dendrodeum extract, favored the healing of burn injuries in this experimental model, with an increase of fibroblasts, collagen fibers, and blood vessels. S. dendroideum isolated only stimulated the collagenesis. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000300201 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502020000300201 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s0102-865020200030000002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.35 n.3 2020 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126445761593344 |