Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis

Detalhes bibliográficos
Autor(a) principal: Cavallari,Fransérgio Emílio
Data de Publicação: 2012
Outros Autores: Valera,Fabiana Cardoso Pereira, Gallego,Aline Jorge, Malinsky,Rafael Rossell, Küpper,Daniel Salgado, Milanezi,Cristiane, Silva,João Santana da, Tamashiro,Edwin, Anselmo-Lima,Wilma Terezinha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900010
Resumo: PURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa. METHODS: Gene expression was quantified by Real Time PCR in polyps (n=35) and in healthy nasal mucosa (n=15). RESULTS: Eosinophilic polyps showed a higher expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa. CONCLUSION: Eosinophilic polyps present greater expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa.
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spelling Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposisNasal PolypsChemokinesIntercellular Adhesion Molecule-1SinusitisPURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa. METHODS: Gene expression was quantified by Real Time PCR in polyps (n=35) and in healthy nasal mucosa (n=15). RESULTS: Eosinophilic polyps showed a higher expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa. CONCLUSION: Eosinophilic polyps present greater expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2012-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900010Acta Cirúrgica Brasileira v.27 n.9 2012reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502012000900010info:eu-repo/semantics/openAccessCavallari,Fransérgio EmílioValera,Fabiana Cardoso PereiraGallego,Aline JorgeMalinsky,Rafael RossellKüpper,Daniel SalgadoMilanezi,CristianeSilva,João Santana daTamashiro,EdwinAnselmo-Lima,Wilma Terezinhaeng2012-08-27T00:00:00Zoai:scielo:S0102-86502012000900010Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2012-08-27T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
title Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
spellingShingle Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
Cavallari,Fransérgio Emílio
Nasal Polyps
Chemokines
Intercellular Adhesion Molecule-1
Sinusitis
title_short Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
title_full Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
title_fullStr Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
title_full_unstemmed Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
title_sort Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis
author Cavallari,Fransérgio Emílio
author_facet Cavallari,Fransérgio Emílio
Valera,Fabiana Cardoso Pereira
Gallego,Aline Jorge
Malinsky,Rafael Rossell
Küpper,Daniel Salgado
Milanezi,Cristiane
Silva,João Santana da
Tamashiro,Edwin
Anselmo-Lima,Wilma Terezinha
author_role author
author2 Valera,Fabiana Cardoso Pereira
Gallego,Aline Jorge
Malinsky,Rafael Rossell
Küpper,Daniel Salgado
Milanezi,Cristiane
Silva,João Santana da
Tamashiro,Edwin
Anselmo-Lima,Wilma Terezinha
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cavallari,Fransérgio Emílio
Valera,Fabiana Cardoso Pereira
Gallego,Aline Jorge
Malinsky,Rafael Rossell
Küpper,Daniel Salgado
Milanezi,Cristiane
Silva,João Santana da
Tamashiro,Edwin
Anselmo-Lima,Wilma Terezinha
dc.subject.por.fl_str_mv Nasal Polyps
Chemokines
Intercellular Adhesion Molecule-1
Sinusitis
topic Nasal Polyps
Chemokines
Intercellular Adhesion Molecule-1
Sinusitis
description PURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa. METHODS: Gene expression was quantified by Real Time PCR in polyps (n=35) and in healthy nasal mucosa (n=15). RESULTS: Eosinophilic polyps showed a higher expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa. CONCLUSION: Eosinophilic polyps present greater expression of eotaxin-2 and RANTES, but not of CCR-3, ICAM-1 or LFA-1 compared to control nasal mucosa.
publishDate 2012
dc.date.none.fl_str_mv 2012-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502012000900010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.27 n.9 2012
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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