Topic drug therapy for neuropathic pain

Detalhes bibliográficos
Autor(a) principal: Kraychete,Durval Campos
Data de Publicação: 2016
Outros Autores: Palladini,Mariana Camargo, Castro,Anita Perpétua Carvalho Rocha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Dor
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500095
Resumo: ABSTRACT BACKGROUND AND OBJECTIVES: First line drugs indicated to treat neuropathic pain are few and their use may be limited by the presence of side effects, impairing adherence to treatment. This review aimed at evaluating whether available topic analgesics have clinical efficacy and whether they might be used as alternative or adjuvant to treat neuropathic pain. CONTENTS: The topic effect of NSAIDs, tricyclic antidepressants, capsaicin, ketamine, clonidine and local anesthetics to treat neuropathic pain of different etiologies was evaluated. CONCLUSION: Few studies in the literature validate the use of topic analgesics to treat neuropathic pain. On the other hand, topic 5% lidocaine may be safely used with good analgesic effect and tolerability. The clinical efficacy of topic analgesics may be associated to the choice of the vehicle, to agent concentration, to pain location and to the specific disease.
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spelling Topic drug therapy for neuropathic painAnalgesicsNeuropathic painTopicTreatmentABSTRACT BACKGROUND AND OBJECTIVES: First line drugs indicated to treat neuropathic pain are few and their use may be limited by the presence of side effects, impairing adherence to treatment. This review aimed at evaluating whether available topic analgesics have clinical efficacy and whether they might be used as alternative or adjuvant to treat neuropathic pain. CONTENTS: The topic effect of NSAIDs, tricyclic antidepressants, capsaicin, ketamine, clonidine and local anesthetics to treat neuropathic pain of different etiologies was evaluated. CONCLUSION: Few studies in the literature validate the use of topic analgesics to treat neuropathic pain. On the other hand, topic 5% lidocaine may be safely used with good analgesic effect and tolerability. The clinical efficacy of topic analgesics may be associated to the choice of the vehicle, to agent concentration, to pain location and to the specific disease.Sociedade Brasileira para o Estudo da Dor2016-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132016000500095Revista Dor v.17 suppl.1 2016reponame:Revista Dorinstname:Sociedade Brasileira para o Estudo da Dor (SBED)instacron:SBED10.5935/1806-0013.20160058info:eu-repo/semantics/openAccessKraychete,Durval CamposPalladini,Mariana CamargoCastro,Anita Perpétua Carvalho Rochaeng2016-09-22T00:00:00Zoai:scielo:S1806-00132016000500095Revistahttps://www.scielo.br/j/rdor/ONGhttps://old.scielo.br/oai/scielo-oai.phpdor@dor.org.br||dor@dor.org.br2317-63931806-0013opendoar:2016-09-22T00:00Revista Dor - Sociedade Brasileira para o Estudo da Dor (SBED)false
dc.title.none.fl_str_mv Topic drug therapy for neuropathic pain
title Topic drug therapy for neuropathic pain
spellingShingle Topic drug therapy for neuropathic pain
Kraychete,Durval Campos
Analgesics
Neuropathic pain
Topic
Treatment
title_short Topic drug therapy for neuropathic pain
title_full Topic drug therapy for neuropathic pain
title_fullStr Topic drug therapy for neuropathic pain
title_full_unstemmed Topic drug therapy for neuropathic pain
title_sort Topic drug therapy for neuropathic pain
author Kraychete,Durval Campos
author_facet Kraychete,Durval Campos
Palladini,Mariana Camargo
Castro,Anita Perpétua Carvalho Rocha
author_role author
author2 Palladini,Mariana Camargo
Castro,Anita Perpétua Carvalho Rocha
author2_role author
author
dc.contributor.author.fl_str_mv Kraychete,Durval Campos
Palladini,Mariana Camargo
Castro,Anita Perpétua Carvalho Rocha
dc.subject.por.fl_str_mv Analgesics
Neuropathic pain
Topic
Treatment
topic Analgesics
Neuropathic pain
Topic
Treatment
description ABSTRACT BACKGROUND AND OBJECTIVES: First line drugs indicated to treat neuropathic pain are few and their use may be limited by the presence of side effects, impairing adherence to treatment. This review aimed at evaluating whether available topic analgesics have clinical efficacy and whether they might be used as alternative or adjuvant to treat neuropathic pain. CONTENTS: The topic effect of NSAIDs, tricyclic antidepressants, capsaicin, ketamine, clonidine and local anesthetics to treat neuropathic pain of different etiologies was evaluated. CONCLUSION: Few studies in the literature validate the use of topic analgesics to treat neuropathic pain. On the other hand, topic 5% lidocaine may be safely used with good analgesic effect and tolerability. The clinical efficacy of topic analgesics may be associated to the choice of the vehicle, to agent concentration, to pain location and to the specific disease.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/1806-0013.20160058
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dc.publisher.none.fl_str_mv Sociedade Brasileira para o Estudo da Dor
publisher.none.fl_str_mv Sociedade Brasileira para o Estudo da Dor
dc.source.none.fl_str_mv Revista Dor v.17 suppl.1 2016
reponame:Revista Dor
instname:Sociedade Brasileira para o Estudo da Dor (SBED)
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reponame_str Revista Dor
collection Revista Dor
repository.name.fl_str_mv Revista Dor - Sociedade Brasileira para o Estudo da Dor (SBED)
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