Clinical evaluation of different epinephrine concentrations for local dental anesthesia
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Dor |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100001 |
Resumo: | BACKGROUND AND OBJECTIVES: Clinical trials comparing lidocaine associated to different epinephrine concentrations are scarce. This study aimed at comparing cardiovascular parameters, anesthetic efficacy and level of discomfort during the injection of two 2% lidocaine solutions associated to 1:100,000 or 1:200,000 epinephrine. METHODS: Participated in this cross-sectional double blind study 30 patients (24.3±4.7 years) who were submitted to anamnesis, vital signs evaluation and baseline threshold measurement of right upper canine tooth. In each clinical session, with 15 days interval, 1.8mL of one of the anesthetic solutions were administered. Anesthetic efficacy was measured with electric stimulation and vital parameters were evaluated in three periods: 5 minutes before, during and soon after anesthesia. At the end of each session, the visual analog scale was applied to evaluate injection pain sensitivity, which was repeated 24h later. RESULTS: All volunteers had satisfactory pressure levels to carry out the trial. There has been no statistically significant differences in systolic blood pressure (p=0.33), diastolic blood pressure (p=0.1505), heart rate (p=0.9464) and oxygen saturation (p=0.9297) considering each local anesthetic solution in each moment (during and after anesthesia). Formulations of 2% lidocaine with 1:100,000 and 1:200,000 epinephrine have shown no statistical differences for all anesthetic parameters (p>0.05). CONCLUSION: Considering the volume used in this study, decreased epinephrine concentration on lidocaine solution has not affected its clinical efficacy and has not influenced cardiovascular parameters. |
id |
SBED-1_c28ad92b90801d5a6f6fcf013f42bd98 |
---|---|
oai_identifier_str |
oai:scielo:S1806-00132015000100001 |
network_acronym_str |
SBED-1 |
network_name_str |
Revista Dor |
repository_id_str |
|
spelling |
Clinical evaluation of different epinephrine concentrations for local dental anesthesiaEpinephrineLocal anesthesiaVasoconstrictors BACKGROUND AND OBJECTIVES: Clinical trials comparing lidocaine associated to different epinephrine concentrations are scarce. This study aimed at comparing cardiovascular parameters, anesthetic efficacy and level of discomfort during the injection of two 2% lidocaine solutions associated to 1:100,000 or 1:200,000 epinephrine. METHODS: Participated in this cross-sectional double blind study 30 patients (24.3±4.7 years) who were submitted to anamnesis, vital signs evaluation and baseline threshold measurement of right upper canine tooth. In each clinical session, with 15 days interval, 1.8mL of one of the anesthetic solutions were administered. Anesthetic efficacy was measured with electric stimulation and vital parameters were evaluated in three periods: 5 minutes before, during and soon after anesthesia. At the end of each session, the visual analog scale was applied to evaluate injection pain sensitivity, which was repeated 24h later. RESULTS: All volunteers had satisfactory pressure levels to carry out the trial. There has been no statistically significant differences in systolic blood pressure (p=0.33), diastolic blood pressure (p=0.1505), heart rate (p=0.9464) and oxygen saturation (p=0.9297) considering each local anesthetic solution in each moment (during and after anesthesia). Formulations of 2% lidocaine with 1:100,000 and 1:200,000 epinephrine have shown no statistical differences for all anesthetic parameters (p>0.05). CONCLUSION: Considering the volume used in this study, decreased epinephrine concentration on lidocaine solution has not affected its clinical efficacy and has not influenced cardiovascular parameters. Sociedade Brasileira para o Estudo da Dor2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100001Revista Dor v.16 n.1 2015reponame:Revista Dorinstname:Sociedade Brasileira para o Estudo da Dor (SBED)instacron:SBED10.5935/1806-0013.20150001info:eu-repo/semantics/openAccessCaldas,Cristina SaragiottoBergamaschi,Cristiane de CássiaSucci,Guilherme de MenezesMotta,Rogério Heládio LopesRamacciato,Juliana Camaeng2015-08-04T00:00:00Zoai:scielo:S1806-00132015000100001Revistahttps://www.scielo.br/j/rdor/ONGhttps://old.scielo.br/oai/scielo-oai.phpdor@dor.org.br||dor@dor.org.br2317-63931806-0013opendoar:2015-08-04T00:00Revista Dor - Sociedade Brasileira para o Estudo da Dor (SBED)false |
dc.title.none.fl_str_mv |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
title |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
spellingShingle |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia Caldas,Cristina Saragiotto Epinephrine Local anesthesia Vasoconstrictors |
title_short |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
title_full |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
title_fullStr |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
title_full_unstemmed |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
title_sort |
Clinical evaluation of different epinephrine concentrations for local dental anesthesia |
author |
Caldas,Cristina Saragiotto |
author_facet |
Caldas,Cristina Saragiotto Bergamaschi,Cristiane de Cássia Succi,Guilherme de Menezes Motta,Rogério Heládio Lopes Ramacciato,Juliana Cama |
author_role |
author |
author2 |
Bergamaschi,Cristiane de Cássia Succi,Guilherme de Menezes Motta,Rogério Heládio Lopes Ramacciato,Juliana Cama |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Caldas,Cristina Saragiotto Bergamaschi,Cristiane de Cássia Succi,Guilherme de Menezes Motta,Rogério Heládio Lopes Ramacciato,Juliana Cama |
dc.subject.por.fl_str_mv |
Epinephrine Local anesthesia Vasoconstrictors |
topic |
Epinephrine Local anesthesia Vasoconstrictors |
description |
BACKGROUND AND OBJECTIVES: Clinical trials comparing lidocaine associated to different epinephrine concentrations are scarce. This study aimed at comparing cardiovascular parameters, anesthetic efficacy and level of discomfort during the injection of two 2% lidocaine solutions associated to 1:100,000 or 1:200,000 epinephrine. METHODS: Participated in this cross-sectional double blind study 30 patients (24.3±4.7 years) who were submitted to anamnesis, vital signs evaluation and baseline threshold measurement of right upper canine tooth. In each clinical session, with 15 days interval, 1.8mL of one of the anesthetic solutions were administered. Anesthetic efficacy was measured with electric stimulation and vital parameters were evaluated in three periods: 5 minutes before, during and soon after anesthesia. At the end of each session, the visual analog scale was applied to evaluate injection pain sensitivity, which was repeated 24h later. RESULTS: All volunteers had satisfactory pressure levels to carry out the trial. There has been no statistically significant differences in systolic blood pressure (p=0.33), diastolic blood pressure (p=0.1505), heart rate (p=0.9464) and oxygen saturation (p=0.9297) considering each local anesthetic solution in each moment (during and after anesthesia). Formulations of 2% lidocaine with 1:100,000 and 1:200,000 epinephrine have shown no statistical differences for all anesthetic parameters (p>0.05). CONCLUSION: Considering the volume used in this study, decreased epinephrine concentration on lidocaine solution has not affected its clinical efficacy and has not influenced cardiovascular parameters. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100001 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-00132015000100001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/1806-0013.20150001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Estudo da Dor |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Estudo da Dor |
dc.source.none.fl_str_mv |
Revista Dor v.16 n.1 2015 reponame:Revista Dor instname:Sociedade Brasileira para o Estudo da Dor (SBED) instacron:SBED |
instname_str |
Sociedade Brasileira para o Estudo da Dor (SBED) |
instacron_str |
SBED |
institution |
SBED |
reponame_str |
Revista Dor |
collection |
Revista Dor |
repository.name.fl_str_mv |
Revista Dor - Sociedade Brasileira para o Estudo da Dor (SBED) |
repository.mail.fl_str_mv |
dor@dor.org.br||dor@dor.org.br |
_version_ |
1752126254955364352 |