Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de Endocrinologia e Metabolismo (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512 |
Resumo: | ABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes. |
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Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort studyMild COVID-19noncritical COVID-19adultsfollow-upoutpatientshospitalizationABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.Sociedade Brasileira de Endocrinologia e Metabologia2022-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512Archives of Endocrinology and Metabolism v.66 n.4 2022reponame:Arquivos de Endocrinologia e Metabolismo (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.20945/2359-3997000000486info:eu-repo/semantics/openAccessSartor,Ivaine Tais SauthierDavid,Caroline Nespolo deTelo,Gabriela HeidenZavaglia,Gabriela OliveiraFernandes,Ingrid RodriguesKern,Luciane BeatrizPolese-Bonatto,MárciaAzevedo,Thaís RauppSantos,Amanda PazAlmeida,Walquiria Aparecida Ferreira dePorto,Victor Bertollo GomesVarela,Fernanda HammesScotta,Marcelo ComerlatoRosa,Regis GoulartStein,Renato T.eng2022-09-27T00:00:00Zoai:scielo:S2359-39972022000400512Revistahttps://www.aem-sbem.com/https://old.scielo.br/oai/scielo-oai.php||aem.editorial.office@endocrino.org.br2359-42922359-3997opendoar:2022-09-27T00:00Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false |
dc.title.none.fl_str_mv |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
title |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
spellingShingle |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study Sartor,Ivaine Tais Sauthier Mild COVID-19 noncritical COVID-19 adults follow-up outpatients hospitalization |
title_short |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
title_full |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
title_fullStr |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
title_full_unstemmed |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
title_sort |
Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study |
author |
Sartor,Ivaine Tais Sauthier |
author_facet |
Sartor,Ivaine Tais Sauthier David,Caroline Nespolo de Telo,Gabriela Heiden Zavaglia,Gabriela Oliveira Fernandes,Ingrid Rodrigues Kern,Luciane Beatriz Polese-Bonatto,Márcia Azevedo,Thaís Raupp Santos,Amanda Paz Almeida,Walquiria Aparecida Ferreira de Porto,Victor Bertollo Gomes Varela,Fernanda Hammes Scotta,Marcelo Comerlato Rosa,Regis Goulart Stein,Renato T. |
author_role |
author |
author2 |
David,Caroline Nespolo de Telo,Gabriela Heiden Zavaglia,Gabriela Oliveira Fernandes,Ingrid Rodrigues Kern,Luciane Beatriz Polese-Bonatto,Márcia Azevedo,Thaís Raupp Santos,Amanda Paz Almeida,Walquiria Aparecida Ferreira de Porto,Victor Bertollo Gomes Varela,Fernanda Hammes Scotta,Marcelo Comerlato Rosa,Regis Goulart Stein,Renato T. |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sartor,Ivaine Tais Sauthier David,Caroline Nespolo de Telo,Gabriela Heiden Zavaglia,Gabriela Oliveira Fernandes,Ingrid Rodrigues Kern,Luciane Beatriz Polese-Bonatto,Márcia Azevedo,Thaís Raupp Santos,Amanda Paz Almeida,Walquiria Aparecida Ferreira de Porto,Victor Bertollo Gomes Varela,Fernanda Hammes Scotta,Marcelo Comerlato Rosa,Regis Goulart Stein,Renato T. |
dc.subject.por.fl_str_mv |
Mild COVID-19 noncritical COVID-19 adults follow-up outpatients hospitalization |
topic |
Mild COVID-19 noncritical COVID-19 adults follow-up outpatients hospitalization |
description |
ABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.20945/2359-3997000000486 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
dc.source.none.fl_str_mv |
Archives of Endocrinology and Metabolism v.66 n.4 2022 reponame:Arquivos de Endocrinologia e Metabolismo (Online) instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) instacron:SBEM |
instname_str |
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) |
instacron_str |
SBEM |
institution |
SBEM |
reponame_str |
Arquivos de Endocrinologia e Metabolismo (Online) |
collection |
Arquivos de Endocrinologia e Metabolismo (Online) |
repository.name.fl_str_mv |
Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) |
repository.mail.fl_str_mv |
||aem.editorial.office@endocrino.org.br |
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