Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study

Detalhes bibliográficos
Autor(a) principal: Sartor,Ivaine Tais Sauthier
Data de Publicação: 2022
Outros Autores: David,Caroline Nespolo de, Telo,Gabriela Heiden, Zavaglia,Gabriela Oliveira, Fernandes,Ingrid Rodrigues, Kern,Luciane Beatriz, Polese-Bonatto,Márcia, Azevedo,Thaís Raupp, Santos,Amanda Paz, Almeida,Walquiria Aparecida Ferreira de, Porto,Victor Bertollo Gomes, Varela,Fernanda Hammes, Scotta,Marcelo Comerlato, Rosa,Regis Goulart, Stein,Renato T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de Endocrinologia e Metabolismo (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512
Resumo: ABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.
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spelling Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort studyMild COVID-19noncritical COVID-19adultsfollow-upoutpatientshospitalizationABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.Sociedade Brasileira de Endocrinologia e Metabologia2022-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512Archives of Endocrinology and Metabolism v.66 n.4 2022reponame:Arquivos de Endocrinologia e Metabolismo (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.20945/2359-3997000000486info:eu-repo/semantics/openAccessSartor,Ivaine Tais SauthierDavid,Caroline Nespolo deTelo,Gabriela HeidenZavaglia,Gabriela OliveiraFernandes,Ingrid RodriguesKern,Luciane BeatrizPolese-Bonatto,MárciaAzevedo,Thaís RauppSantos,Amanda PazAlmeida,Walquiria Aparecida Ferreira dePorto,Victor Bertollo GomesVarela,Fernanda HammesScotta,Marcelo ComerlatoRosa,Regis GoulartStein,Renato T.eng2022-09-27T00:00:00Zoai:scielo:S2359-39972022000400512Revistahttps://www.aem-sbem.com/https://old.scielo.br/oai/scielo-oai.php||aem.editorial.office@endocrino.org.br2359-42922359-3997opendoar:2022-09-27T00:00Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
title Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
spellingShingle Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
Sartor,Ivaine Tais Sauthier
Mild COVID-19
noncritical COVID-19
adults
follow-up
outpatients
hospitalization
title_short Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
title_full Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
title_fullStr Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
title_full_unstemmed Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
title_sort Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
author Sartor,Ivaine Tais Sauthier
author_facet Sartor,Ivaine Tais Sauthier
David,Caroline Nespolo de
Telo,Gabriela Heiden
Zavaglia,Gabriela Oliveira
Fernandes,Ingrid Rodrigues
Kern,Luciane Beatriz
Polese-Bonatto,Márcia
Azevedo,Thaís Raupp
Santos,Amanda Paz
Almeida,Walquiria Aparecida Ferreira de
Porto,Victor Bertollo Gomes
Varela,Fernanda Hammes
Scotta,Marcelo Comerlato
Rosa,Regis Goulart
Stein,Renato T.
author_role author
author2 David,Caroline Nespolo de
Telo,Gabriela Heiden
Zavaglia,Gabriela Oliveira
Fernandes,Ingrid Rodrigues
Kern,Luciane Beatriz
Polese-Bonatto,Márcia
Azevedo,Thaís Raupp
Santos,Amanda Paz
Almeida,Walquiria Aparecida Ferreira de
Porto,Victor Bertollo Gomes
Varela,Fernanda Hammes
Scotta,Marcelo Comerlato
Rosa,Regis Goulart
Stein,Renato T.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sartor,Ivaine Tais Sauthier
David,Caroline Nespolo de
Telo,Gabriela Heiden
Zavaglia,Gabriela Oliveira
Fernandes,Ingrid Rodrigues
Kern,Luciane Beatriz
Polese-Bonatto,Márcia
Azevedo,Thaís Raupp
Santos,Amanda Paz
Almeida,Walquiria Aparecida Ferreira de
Porto,Victor Bertollo Gomes
Varela,Fernanda Hammes
Scotta,Marcelo Comerlato
Rosa,Regis Goulart
Stein,Renato T.
dc.subject.por.fl_str_mv Mild COVID-19
noncritical COVID-19
adults
follow-up
outpatients
hospitalization
topic Mild COVID-19
noncritical COVID-19
adults
follow-up
outpatients
hospitalization
description ABSTRACT Objective: To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects and methods: Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization. Results: A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization. Conclusion: Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000400512
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.20945/2359-3997000000486
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Archives of Endocrinology and Metabolism v.66 n.4 2022
reponame:Arquivos de Endocrinologia e Metabolismo (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
instname_str Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron_str SBEM
institution SBEM
reponame_str Arquivos de Endocrinologia e Metabolismo (Online)
collection Arquivos de Endocrinologia e Metabolismo (Online)
repository.name.fl_str_mv Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
repository.mail.fl_str_mv ||aem.editorial.office@endocrino.org.br
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