Seasonal variation of haemoglobin A1c in a Portuguese adult population

Detalhes bibliográficos
Autor(a) principal: Pereira,Maria Teresa Rocha e Pinho
Data de Publicação: 2015
Outros Autores: Lira,Domingos, Bacelar,Conceição, Oliveira,José Carlos, Carvalho,André Couto de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de Endocrinologia e Metabolismo (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300231
Resumo: Objective Haemoglobin A1c (Hb A1c) is routinely used for monitoring glycemic control in patients with diabetes. Hb A1c seasonal fluctuations can be directly related to different biological, geographical and cultural influences. Our purpose was to evaluate seasonal variation of Hb A1c in a hospital-based adult population over a period of 5 years.Materials and methods We analyzed retrospectively monthly Hb A1c mean values (DCCT, %) based on all the assays performed to adult patients at a tertiary care university Portuguese hospital between 2008-2012.Results We obtained 62,384 Hb A1c valid measurements, with a peak level found in January-February (7.1%), a trough in August-October (6.8%) and an average peak-to-trough amplitude value of 0.3%. This trend was observed in both genders and age subgroups evaluated.Conclusions There is a Hb A1c circannual seasonal pattern with peak levels occurring in winter months in this Portuguese population. This finding should be recognized in daily clinical practice to warrant better clinical and epidemiological interpretation of Hb A1c values. Arch Endocrinol Metab. 2015;59(3):231-5
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spelling Seasonal variation of haemoglobin A1c in a Portuguese adult populationSeasonal variationhaemoglobin A1cblood glucoseObjective Haemoglobin A1c (Hb A1c) is routinely used for monitoring glycemic control in patients with diabetes. Hb A1c seasonal fluctuations can be directly related to different biological, geographical and cultural influences. Our purpose was to evaluate seasonal variation of Hb A1c in a hospital-based adult population over a period of 5 years.Materials and methods We analyzed retrospectively monthly Hb A1c mean values (DCCT, %) based on all the assays performed to adult patients at a tertiary care university Portuguese hospital between 2008-2012.Results We obtained 62,384 Hb A1c valid measurements, with a peak level found in January-February (7.1%), a trough in August-October (6.8%) and an average peak-to-trough amplitude value of 0.3%. This trend was observed in both genders and age subgroups evaluated.Conclusions There is a Hb A1c circannual seasonal pattern with peak levels occurring in winter months in this Portuguese population. This finding should be recognized in daily clinical practice to warrant better clinical and epidemiological interpretation of Hb A1c values. Arch Endocrinol Metab. 2015;59(3):231-5Sociedade Brasileira de Endocrinologia e Metabologia2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300231Archives of Endocrinology and Metabolism v.59 n.3 2015reponame:Arquivos de Endocrinologia e Metabolismo (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/2359-3997000000043info:eu-repo/semantics/openAccessPereira,Maria Teresa Rocha e PinhoLira,DomingosBacelar,ConceiçãoOliveira,José CarlosCarvalho,André Couto deeng2015-07-03T00:00:00Zoai:scielo:S2359-39972015000300231Revistahttps://www.aem-sbem.com/https://old.scielo.br/oai/scielo-oai.php||aem.editorial.office@endocrino.org.br2359-42922359-3997opendoar:2015-07-03T00:00Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Seasonal variation of haemoglobin A1c in a Portuguese adult population
title Seasonal variation of haemoglobin A1c in a Portuguese adult population
spellingShingle Seasonal variation of haemoglobin A1c in a Portuguese adult population
Pereira,Maria Teresa Rocha e Pinho
Seasonal variation
haemoglobin A1c
blood glucose
title_short Seasonal variation of haemoglobin A1c in a Portuguese adult population
title_full Seasonal variation of haemoglobin A1c in a Portuguese adult population
title_fullStr Seasonal variation of haemoglobin A1c in a Portuguese adult population
title_full_unstemmed Seasonal variation of haemoglobin A1c in a Portuguese adult population
title_sort Seasonal variation of haemoglobin A1c in a Portuguese adult population
author Pereira,Maria Teresa Rocha e Pinho
author_facet Pereira,Maria Teresa Rocha e Pinho
Lira,Domingos
Bacelar,Conceição
Oliveira,José Carlos
Carvalho,André Couto de
author_role author
author2 Lira,Domingos
Bacelar,Conceição
Oliveira,José Carlos
Carvalho,André Couto de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Maria Teresa Rocha e Pinho
Lira,Domingos
Bacelar,Conceição
Oliveira,José Carlos
Carvalho,André Couto de
dc.subject.por.fl_str_mv Seasonal variation
haemoglobin A1c
blood glucose
topic Seasonal variation
haemoglobin A1c
blood glucose
description Objective Haemoglobin A1c (Hb A1c) is routinely used for monitoring glycemic control in patients with diabetes. Hb A1c seasonal fluctuations can be directly related to different biological, geographical and cultural influences. Our purpose was to evaluate seasonal variation of Hb A1c in a hospital-based adult population over a period of 5 years.Materials and methods We analyzed retrospectively monthly Hb A1c mean values (DCCT, %) based on all the assays performed to adult patients at a tertiary care university Portuguese hospital between 2008-2012.Results We obtained 62,384 Hb A1c valid measurements, with a peak level found in January-February (7.1%), a trough in August-October (6.8%) and an average peak-to-trough amplitude value of 0.3%. This trend was observed in both genders and age subgroups evaluated.Conclusions There is a Hb A1c circannual seasonal pattern with peak levels occurring in winter months in this Portuguese population. This finding should be recognized in daily clinical practice to warrant better clinical and epidemiological interpretation of Hb A1c values. Arch Endocrinol Metab. 2015;59(3):231-5
publishDate 2015
dc.date.none.fl_str_mv 2015-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300231
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300231
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/2359-3997000000043
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Archives of Endocrinology and Metabolism v.59 n.3 2015
reponame:Arquivos de Endocrinologia e Metabolismo (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
instname_str Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron_str SBEM
institution SBEM
reponame_str Arquivos de Endocrinologia e Metabolismo (Online)
collection Arquivos de Endocrinologia e Metabolismo (Online)
repository.name.fl_str_mv Arquivos de Endocrinologia e Metabolismo (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
repository.mail.fl_str_mv ||aem.editorial.office@endocrino.org.br
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