Cyclic ACTH-secreting thymic carcinoid: a case report and review of the literature

• Autor(a) principal: Lamback,Elisa B.
• Data de Publicação: 2021
• Outros Autores: Almeida,Sérgio Altino de, Terra,Ricardo, Ferreira,Carlos Gil, Capelozzi,Vera Luiza, Haddad,Rui, Gadelha,Mônica R.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Arquivos de Endocrinologia e Metabolismo (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972021000400512

SUMMARY Cyclic Cushing's syndrome (CS) due to thymic carcinoid is a rare disorder. We report a case of cyclic CS due to ectopic adrenocorticotropic hormone (ACTH)-secreting atypical thymic carcinoid tumor and reviewed similar cases published in the literature. Our patient had hypercortisolemia lasting approximately one month, followed by normal cortisol secretion, with relapse one year later. Histopathology revealed an atypical ACTH-positive thymic carcinoid. Ectopic CS can be derived from atypical thymic carcinoids, which can be aggressive tumors with early relapse, suggesting that this type of tumor probably needs aggressive treatment.