Epidemiological and molecular mechanisms aspects linking obesity and cancer

Detalhes bibliográficos
Autor(a) principal: Osório-Costa,Felipe
Data de Publicação: 2009
Outros Autores: Rocha,Guilherme Z., Dias,Marília M., Carvalheira,José B. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000200013
Resumo: About 25% of cancer cases globally are due to excess weight and a sedentary lifestyle. These results are alarming, as the world knows a pandemy of obesity and, in consequence, insulin resistance. Obesity may increase risk for various cancers by several mechanisms, including increasing sex and metabolic hormones, and inflammation. Here, we present a review of epidemiological and molecular evidences linking obesity and cancer - particularly colorectal, post-menopausal breast, endometrial, pancreatic, high grade prostate, hepatocellular, gallbladder, kidney and esophageal adenocarcinoma. The expected striking increase in the incidence of cancer in the near future related to obesity turns the knowledge of this field of great impact as it is needed to the development of strategies to prevent and treat this disease.
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spelling Epidemiological and molecular mechanisms aspects linking obesity and cancerNeoplasmsobesityoverweightinsulin resistanceAbout 25% of cancer cases globally are due to excess weight and a sedentary lifestyle. These results are alarming, as the world knows a pandemy of obesity and, in consequence, insulin resistance. Obesity may increase risk for various cancers by several mechanisms, including increasing sex and metabolic hormones, and inflammation. Here, we present a review of epidemiological and molecular evidences linking obesity and cancer - particularly colorectal, post-menopausal breast, endometrial, pancreatic, high grade prostate, hepatocellular, gallbladder, kidney and esophageal adenocarcinoma. The expected striking increase in the incidence of cancer in the near future related to obesity turns the knowledge of this field of great impact as it is needed to the development of strategies to prevent and treat this disease.Sociedade Brasileira de Endocrinologia e Metabologia2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000200013Arquivos Brasileiros de Endocrinologia & Metabologia v.53 n.2 2009reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/S0004-27302009000200013info:eu-repo/semantics/openAccessOsório-Costa,FelipeRocha,Guilherme Z.Dias,Marília M.Carvalheira,José B. C.eng2015-07-02T00:00:00Zoai:scielo:S0004-27302009000200013Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2015-07-02T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Epidemiological and molecular mechanisms aspects linking obesity and cancer
title Epidemiological and molecular mechanisms aspects linking obesity and cancer
spellingShingle Epidemiological and molecular mechanisms aspects linking obesity and cancer
Osório-Costa,Felipe
Neoplasms
obesity
overweight
insulin resistance
title_short Epidemiological and molecular mechanisms aspects linking obesity and cancer
title_full Epidemiological and molecular mechanisms aspects linking obesity and cancer
title_fullStr Epidemiological and molecular mechanisms aspects linking obesity and cancer
title_full_unstemmed Epidemiological and molecular mechanisms aspects linking obesity and cancer
title_sort Epidemiological and molecular mechanisms aspects linking obesity and cancer
author Osório-Costa,Felipe
author_facet Osório-Costa,Felipe
Rocha,Guilherme Z.
Dias,Marília M.
Carvalheira,José B. C.
author_role author
author2 Rocha,Guilherme Z.
Dias,Marília M.
Carvalheira,José B. C.
author2_role author
author
author
dc.contributor.author.fl_str_mv Osório-Costa,Felipe
Rocha,Guilherme Z.
Dias,Marília M.
Carvalheira,José B. C.
dc.subject.por.fl_str_mv Neoplasms
obesity
overweight
insulin resistance
topic Neoplasms
obesity
overweight
insulin resistance
description About 25% of cancer cases globally are due to excess weight and a sedentary lifestyle. These results are alarming, as the world knows a pandemy of obesity and, in consequence, insulin resistance. Obesity may increase risk for various cancers by several mechanisms, including increasing sex and metabolic hormones, and inflammation. Here, we present a review of epidemiological and molecular evidences linking obesity and cancer - particularly colorectal, post-menopausal breast, endometrial, pancreatic, high grade prostate, hepatocellular, gallbladder, kidney and esophageal adenocarcinoma. The expected striking increase in the incidence of cancer in the near future related to obesity turns the knowledge of this field of great impact as it is needed to the development of strategies to prevent and treat this disease.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000200013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000200013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27302009000200013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia v.53 n.2 2009
reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
instname_str Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron_str SBEM
institution SBEM
reponame_str Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
collection Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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