Bone markers and osteoporosis therapy

Detalhes bibliográficos
Autor(a) principal: Bandeira,Francisco
Data de Publicação: 2014
Outros Autores: Costa,Aline G., Soares Filho,Manoel Aderson, Pimentel,Larissa, Lima,Lourena, Bilezikian,John P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500504
Resumo: Several factors are involved in determining bone quality including bone density, bone turnover, the extent of trabecular bone connectivity, cortical porosity and geometry. Metabolically active and in a continuous process of remodeling, approximately 20% of bone tissue is renewed annually. Bone turn over markers (BTM) are frequently used in clinical trials and to provide valid information about the effectiveness of osteoporosis treatment, reflecting the state of bone metabolism and its response to treatment, although they are not useful alone to estimate bone loss. In this review the behavior of BTM from different clinical trials or different osteoporotic drugs will be addressed.
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spelling Bone markers and osteoporosis therapyBone markersosteoporosisbone densitySeveral factors are involved in determining bone quality including bone density, bone turnover, the extent of trabecular bone connectivity, cortical porosity and geometry. Metabolically active and in a continuous process of remodeling, approximately 20% of bone tissue is renewed annually. Bone turn over markers (BTM) are frequently used in clinical trials and to provide valid information about the effectiveness of osteoporosis treatment, reflecting the state of bone metabolism and its response to treatment, although they are not useful alone to estimate bone loss. In this review the behavior of BTM from different clinical trials or different osteoporotic drugs will be addressed.Sociedade Brasileira de Endocrinologia e Metabologia2014-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500504Arquivos Brasileiros de Endocrinologia & Metabologia v.58 n.5 2014reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/0004-2730000003384info:eu-repo/semantics/openAccessBandeira,FranciscoCosta,Aline G.Soares Filho,Manoel AdersonPimentel,LarissaLima,LourenaBilezikian,John P.eng2014-08-19T00:00:00Zoai:scielo:S0004-27302014000500504Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2014-08-19T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Bone markers and osteoporosis therapy
title Bone markers and osteoporosis therapy
spellingShingle Bone markers and osteoporosis therapy
Bandeira,Francisco
Bone markers
osteoporosis
bone density
title_short Bone markers and osteoporosis therapy
title_full Bone markers and osteoporosis therapy
title_fullStr Bone markers and osteoporosis therapy
title_full_unstemmed Bone markers and osteoporosis therapy
title_sort Bone markers and osteoporosis therapy
author Bandeira,Francisco
author_facet Bandeira,Francisco
Costa,Aline G.
Soares Filho,Manoel Aderson
Pimentel,Larissa
Lima,Lourena
Bilezikian,John P.
author_role author
author2 Costa,Aline G.
Soares Filho,Manoel Aderson
Pimentel,Larissa
Lima,Lourena
Bilezikian,John P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Bandeira,Francisco
Costa,Aline G.
Soares Filho,Manoel Aderson
Pimentel,Larissa
Lima,Lourena
Bilezikian,John P.
dc.subject.por.fl_str_mv Bone markers
osteoporosis
bone density
topic Bone markers
osteoporosis
bone density
description Several factors are involved in determining bone quality including bone density, bone turnover, the extent of trabecular bone connectivity, cortical porosity and geometry. Metabolically active and in a continuous process of remodeling, approximately 20% of bone tissue is renewed annually. Bone turn over markers (BTM) are frequently used in clinical trials and to provide valid information about the effectiveness of osteoporosis treatment, reflecting the state of bone metabolism and its response to treatment, although they are not useful alone to estimate bone loss. In this review the behavior of BTM from different clinical trials or different osteoporotic drugs will be addressed.
publishDate 2014
dc.date.none.fl_str_mv 2014-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500504
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000500504
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-2730000003384
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia v.58 n.5 2014
reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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reponame_str Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
collection Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
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