Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300009 |
Resumo: | The essential oils (EO) of Salix aegyptiaca L., Salicaceae (SA), leaves were extracted using the hydrodistillation method and their chemical composition was further determined by GC-MS. 1,4-Dimethoxybenzene was the main isolated compound. Other major isolated constitutes were phenylethyl alcohol, carvone, citronellol, methyleugenol, eugenol, n-tetradecane and 4'-methoxyacetophenone. Twenty rabbits were equally divided into four groups: Normal control (NC) which fed a standard diet and three cholesterol-fed groups: HC, HC+1.0% SA and HC+3.0% SA groups which received 0.0%, 1.0% and 3.0% EO, respectively for four weeks. The serum lipid and lipoprotein profiles and atherogenic index (AI) were measured weekly. The high cholesterol diet significantly raised the TC, LDL-C, VLDL-C, HDL-C, TG and AI level compared with NC group. HC+1.0% SA and HC+3.0% SA groups showed similar results compared with HC group. It can be concluded that the EO of SA leaves could not prevent dyslipidemia that occurred in rabbits following inclusion of cholesterol in diet in both dose-and time-dependent manners. |
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Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit modelSalix aegyptiacahypercholesterolemiaessential oil1,4-dimethoxybenzeneThe essential oils (EO) of Salix aegyptiaca L., Salicaceae (SA), leaves were extracted using the hydrodistillation method and their chemical composition was further determined by GC-MS. 1,4-Dimethoxybenzene was the main isolated compound. Other major isolated constitutes were phenylethyl alcohol, carvone, citronellol, methyleugenol, eugenol, n-tetradecane and 4'-methoxyacetophenone. Twenty rabbits were equally divided into four groups: Normal control (NC) which fed a standard diet and three cholesterol-fed groups: HC, HC+1.0% SA and HC+3.0% SA groups which received 0.0%, 1.0% and 3.0% EO, respectively for four weeks. The serum lipid and lipoprotein profiles and atherogenic index (AI) were measured weekly. The high cholesterol diet significantly raised the TC, LDL-C, VLDL-C, HDL-C, TG and AI level compared with NC group. HC+1.0% SA and HC+3.0% SA groups showed similar results compared with HC group. It can be concluded that the EO of SA leaves could not prevent dyslipidemia that occurred in rabbits following inclusion of cholesterol in diet in both dose-and time-dependent manners.Sociedade Brasileira de Farmacognosia2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300009Revista Brasileira de Farmacognosia v.21 n.3 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000030info:eu-repo/semantics/openAccessKarimi,IsaacHayatgheybi,Hosseinshamspur,TayebehKamalak,AdemPooyanmehr,MehrdadMarandi,Yasereng2011-07-08T00:00:00Zoai:scielo:S0102-695X2011000300009Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-07-08T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
title |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
spellingShingle |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model Karimi,Isaac Salix aegyptiaca hypercholesterolemia essential oil 1,4-dimethoxybenzene |
title_short |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
title_full |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
title_fullStr |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
title_full_unstemmed |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
title_sort |
Chemical composition and effect of an essential oil of Salix aegyptiaca L., Salicaceae, (musk willow) in hypercholesterolemic rabbit model |
author |
Karimi,Isaac |
author_facet |
Karimi,Isaac Hayatgheybi,Hossein shamspur,Tayebeh Kamalak,Adem Pooyanmehr,Mehrdad Marandi,Yaser |
author_role |
author |
author2 |
Hayatgheybi,Hossein shamspur,Tayebeh Kamalak,Adem Pooyanmehr,Mehrdad Marandi,Yaser |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Karimi,Isaac Hayatgheybi,Hossein shamspur,Tayebeh Kamalak,Adem Pooyanmehr,Mehrdad Marandi,Yaser |
dc.subject.por.fl_str_mv |
Salix aegyptiaca hypercholesterolemia essential oil 1,4-dimethoxybenzene |
topic |
Salix aegyptiaca hypercholesterolemia essential oil 1,4-dimethoxybenzene |
description |
The essential oils (EO) of Salix aegyptiaca L., Salicaceae (SA), leaves were extracted using the hydrodistillation method and their chemical composition was further determined by GC-MS. 1,4-Dimethoxybenzene was the main isolated compound. Other major isolated constitutes were phenylethyl alcohol, carvone, citronellol, methyleugenol, eugenol, n-tetradecane and 4'-methoxyacetophenone. Twenty rabbits were equally divided into four groups: Normal control (NC) which fed a standard diet and three cholesterol-fed groups: HC, HC+1.0% SA and HC+3.0% SA groups which received 0.0%, 1.0% and 3.0% EO, respectively for four weeks. The serum lipid and lipoprotein profiles and atherogenic index (AI) were measured weekly. The high cholesterol diet significantly raised the TC, LDL-C, VLDL-C, HDL-C, TG and AI level compared with NC group. HC+1.0% SA and HC+3.0% SA groups showed similar results compared with HC group. It can be concluded that the EO of SA leaves could not prevent dyslipidemia that occurred in rabbits following inclusion of cholesterol in diet in both dose-and time-dependent manners. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300009 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000300009 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2011005000030 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.21 n.3 2011 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122465648115712 |