The role of tannins as antiulcer agents: a fluorescence-imaging based study

Detalhes bibliográficos
Autor(a) principal: Demarque,Daniel P.
Data de Publicação: 2018
Outros Autores: Callejon,Daniel R., Oliveira,Gibson G. de, Silva,Denise B., Carollo,Carlos A., Lopes,Norberto P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2018000400425
Resumo: Abstract Condensed tannins have been used for many years in folk medicine to treat gastric problems. The mechanism of action that explains why tannins improve gastritis symptoms is based on their ability to chelate metals, antioxidant activity, and their complexation power with other molecules. Even though these uses are well-known, the requirements to become an herbal medicine are much more complex. Herein, we analyzed Stryphnodendron rotundifolium Mart., Fabaceae, extract using MALDI for tannin characterization and carried out a fluorescence-imaging study to prove the gastroprotective effects of tannins as coating agents. Through these methods we show that condensed tannins form a gastroprotective layer. Moreover, we revise and discuss other possible mechanisms of action for phenolic-rich plant extracts and their potential in the development of herbal medicines to treat ulcers and gastritis.
id SBFGNOSIA-1_2c416d961944888a88978f336abf0281
oai_identifier_str oai:scielo:S0102-695X2018000400425
network_acronym_str SBFGNOSIA-1
network_name_str Revista Brasileira de Farmacognosia (Online)
repository_id_str
spelling The role of tannins as antiulcer agents: a fluorescence-imaging based studyStomachUlcerGastritisTanninsPhenolicMALDIAbstract Condensed tannins have been used for many years in folk medicine to treat gastric problems. The mechanism of action that explains why tannins improve gastritis symptoms is based on their ability to chelate metals, antioxidant activity, and their complexation power with other molecules. Even though these uses are well-known, the requirements to become an herbal medicine are much more complex. Herein, we analyzed Stryphnodendron rotundifolium Mart., Fabaceae, extract using MALDI for tannin characterization and carried out a fluorescence-imaging study to prove the gastroprotective effects of tannins as coating agents. Through these methods we show that condensed tannins form a gastroprotective layer. Moreover, we revise and discuss other possible mechanisms of action for phenolic-rich plant extracts and their potential in the development of herbal medicines to treat ulcers and gastritis.Sociedade Brasileira de Farmacognosia2018-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2018000400425Revista Brasileira de Farmacognosia v.28 n.4 2018reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2018.03.011info:eu-repo/semantics/openAccessDemarque,Daniel P.Callejon,Daniel R.Oliveira,Gibson G. deSilva,Denise B.Carollo,Carlos A.Lopes,Norberto P.eng2018-08-13T00:00:00Zoai:scielo:S0102-695X2018000400425Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2018-08-13T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv The role of tannins as antiulcer agents: a fluorescence-imaging based study
title The role of tannins as antiulcer agents: a fluorescence-imaging based study
spellingShingle The role of tannins as antiulcer agents: a fluorescence-imaging based study
Demarque,Daniel P.
Stomach
Ulcer
Gastritis
Tannins
Phenolic
MALDI
title_short The role of tannins as antiulcer agents: a fluorescence-imaging based study
title_full The role of tannins as antiulcer agents: a fluorescence-imaging based study
title_fullStr The role of tannins as antiulcer agents: a fluorescence-imaging based study
title_full_unstemmed The role of tannins as antiulcer agents: a fluorescence-imaging based study
title_sort The role of tannins as antiulcer agents: a fluorescence-imaging based study
author Demarque,Daniel P.
author_facet Demarque,Daniel P.
Callejon,Daniel R.
Oliveira,Gibson G. de
Silva,Denise B.
Carollo,Carlos A.
Lopes,Norberto P.
author_role author
author2 Callejon,Daniel R.
Oliveira,Gibson G. de
Silva,Denise B.
Carollo,Carlos A.
Lopes,Norberto P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Demarque,Daniel P.
Callejon,Daniel R.
Oliveira,Gibson G. de
Silva,Denise B.
Carollo,Carlos A.
Lopes,Norberto P.
dc.subject.por.fl_str_mv Stomach
Ulcer
Gastritis
Tannins
Phenolic
MALDI
topic Stomach
Ulcer
Gastritis
Tannins
Phenolic
MALDI
description Abstract Condensed tannins have been used for many years in folk medicine to treat gastric problems. The mechanism of action that explains why tannins improve gastritis symptoms is based on their ability to chelate metals, antioxidant activity, and their complexation power with other molecules. Even though these uses are well-known, the requirements to become an herbal medicine are much more complex. Herein, we analyzed Stryphnodendron rotundifolium Mart., Fabaceae, extract using MALDI for tannin characterization and carried out a fluorescence-imaging study to prove the gastroprotective effects of tannins as coating agents. Through these methods we show that condensed tannins form a gastroprotective layer. Moreover, we revise and discuss other possible mechanisms of action for phenolic-rich plant extracts and their potential in the development of herbal medicines to treat ulcers and gastritis.
publishDate 2018
dc.date.none.fl_str_mv 2018-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2018000400425
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2018000400425
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjp.2018.03.011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.28 n.4 2018
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
_version_ 1752122470981173248

Registros relacionados