Natural products assessed in animal models for orofacial pain – a systematic review
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000100124 |
Resumo: | ABSTRACT Orofacial pain is related to tissues of the head, face, neck and all the intraoral structures; it is rather debilitating to the patient and also difficult to treat. There are relatively few studies dedicated to the use of natural products to alleviate orofacial pain in preclinical experiment models (performed in experimental animals which provide support for clinical trials). Main objectives of the present systematic review summarize the studies on natural products assessed in animal models for orofacial pain seeking to give evidence to future development of new pharmaceutical products to manage the orofacial pain. Our review includes a thorough search of literature using the terms of orofacial pain, facial pain, medicinal plants and natural products. This search was performed using to retrieve English language articles in Medline-PubMed, Scopus and Web of Science. A total of eighteen studies were included in our survey for the inclusion criteria. Firstly, this review identified 210 citations from electronic search, after removal of duplicates and screening for relevant titles and abstracts, a total of eighteen articles were selected to the inclusion criteria established. Our findings suggest that natural products can be a promising or a trump tool for the development of new drugs to treat orofacial pain conditions, but the researchers that deal with experimental preclinical trials of new drugs (including natural products or synthetic drugs) for orofacial pain conditions urgently need to show translational evidence (with clinical approach) of these compounds. |
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Natural products assessed in animal models for orofacial pain – a systematic reviewMedicinal plantsNatural productsOrofacial painPainAnimal modelsABSTRACT Orofacial pain is related to tissues of the head, face, neck and all the intraoral structures; it is rather debilitating to the patient and also difficult to treat. There are relatively few studies dedicated to the use of natural products to alleviate orofacial pain in preclinical experiment models (performed in experimental animals which provide support for clinical trials). Main objectives of the present systematic review summarize the studies on natural products assessed in animal models for orofacial pain seeking to give evidence to future development of new pharmaceutical products to manage the orofacial pain. Our review includes a thorough search of literature using the terms of orofacial pain, facial pain, medicinal plants and natural products. This search was performed using to retrieve English language articles in Medline-PubMed, Scopus and Web of Science. A total of eighteen studies were included in our survey for the inclusion criteria. Firstly, this review identified 210 citations from electronic search, after removal of duplicates and screening for relevant titles and abstracts, a total of eighteen articles were selected to the inclusion criteria established. Our findings suggest that natural products can be a promising or a trump tool for the development of new drugs to treat orofacial pain conditions, but the researchers that deal with experimental preclinical trials of new drugs (including natural products or synthetic drugs) for orofacial pain conditions urgently need to show translational evidence (with clinical approach) of these compounds.Sociedade Brasileira de Farmacognosia2017-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000100124Revista Brasileira de Farmacognosia v.27 n.1 2017reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2016.06.005info:eu-repo/semantics/openAccessSiqueira-Lima,Pollyana S.Silva,Juliane C.Quintans,Jullyana S.S.Antoniolli,Angelo R.Shanmugam,SaravananBarreto,Rosana S.S.Santos,Márcio R.V.Almeida,Jackson R.G.S.Bonjardim,Leonardo R.Menezes,Irwin R.A.Quintans-Júnior,Lucindo J.eng2017-01-10T00:00:00Zoai:scielo:S0102-695X2017000100124Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2017-01-10T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Natural products assessed in animal models for orofacial pain – a systematic review |
title |
Natural products assessed in animal models for orofacial pain – a systematic review |
spellingShingle |
Natural products assessed in animal models for orofacial pain – a systematic review Siqueira-Lima,Pollyana S. Medicinal plants Natural products Orofacial pain Pain Animal models |
title_short |
Natural products assessed in animal models for orofacial pain – a systematic review |
title_full |
Natural products assessed in animal models for orofacial pain – a systematic review |
title_fullStr |
Natural products assessed in animal models for orofacial pain – a systematic review |
title_full_unstemmed |
Natural products assessed in animal models for orofacial pain – a systematic review |
title_sort |
Natural products assessed in animal models for orofacial pain – a systematic review |
author |
Siqueira-Lima,Pollyana S. |
author_facet |
Siqueira-Lima,Pollyana S. Silva,Juliane C. Quintans,Jullyana S.S. Antoniolli,Angelo R. Shanmugam,Saravanan Barreto,Rosana S.S. Santos,Márcio R.V. Almeida,Jackson R.G.S. Bonjardim,Leonardo R. Menezes,Irwin R.A. Quintans-Júnior,Lucindo J. |
author_role |
author |
author2 |
Silva,Juliane C. Quintans,Jullyana S.S. Antoniolli,Angelo R. Shanmugam,Saravanan Barreto,Rosana S.S. Santos,Márcio R.V. Almeida,Jackson R.G.S. Bonjardim,Leonardo R. Menezes,Irwin R.A. Quintans-Júnior,Lucindo J. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Siqueira-Lima,Pollyana S. Silva,Juliane C. Quintans,Jullyana S.S. Antoniolli,Angelo R. Shanmugam,Saravanan Barreto,Rosana S.S. Santos,Márcio R.V. Almeida,Jackson R.G.S. Bonjardim,Leonardo R. Menezes,Irwin R.A. Quintans-Júnior,Lucindo J. |
dc.subject.por.fl_str_mv |
Medicinal plants Natural products Orofacial pain Pain Animal models |
topic |
Medicinal plants Natural products Orofacial pain Pain Animal models |
description |
ABSTRACT Orofacial pain is related to tissues of the head, face, neck and all the intraoral structures; it is rather debilitating to the patient and also difficult to treat. There are relatively few studies dedicated to the use of natural products to alleviate orofacial pain in preclinical experiment models (performed in experimental animals which provide support for clinical trials). Main objectives of the present systematic review summarize the studies on natural products assessed in animal models for orofacial pain seeking to give evidence to future development of new pharmaceutical products to manage the orofacial pain. Our review includes a thorough search of literature using the terms of orofacial pain, facial pain, medicinal plants and natural products. This search was performed using to retrieve English language articles in Medline-PubMed, Scopus and Web of Science. A total of eighteen studies were included in our survey for the inclusion criteria. Firstly, this review identified 210 citations from electronic search, after removal of duplicates and screening for relevant titles and abstracts, a total of eighteen articles were selected to the inclusion criteria established. Our findings suggest that natural products can be a promising or a trump tool for the development of new drugs to treat orofacial pain conditions, but the researchers that deal with experimental preclinical trials of new drugs (including natural products or synthetic drugs) for orofacial pain conditions urgently need to show translational evidence (with clinical approach) of these compounds. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000100124 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2017000100124 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjp.2016.06.005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.27 n.1 2017 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
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1752122470170624000 |