Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600627 |
Resumo: | Abstract Intraspecific variation on meroditerpenoids production by the brown marine alga Stypopodium zonale at four different populations along the Brazilian coast was analyzed using Principal Component Analysis over high-performance liquid chromatography profiles from algae extracts. The ordination of the samples by the similarities of their chromatographic traits showed the existence of three chemotypes: (i) the populations Búzios and Abrolhos which were characterized by the presence of atomaric acid (1), (ii) the population Atol das Rocas which contained the compound stypoldione (2), and (iii) the population Marataízes which was characterized by other peaks that guided the isolation of three new meroditerpenoids stypofuranlactone (3), 10,18-dihydroxy-5′a-desmethyl-5′-acetylatomaric acid (4), and the 10-keto-10-deisopropyliden-5′a-desmethyl-5′-acetylatomaric acid (5) together with the known compound the 10-keto-10-deisopropyliden-atomaric acid (6). The structures and relative stereochemistry of 3, 4 and 5 were elucidated by NMR and MS techniques. The observed chemical differences among populations of S. zonale can be related to its geographic distribution and can open an avenue to the discovery of new compounds in algae. |
id |
SBFGNOSIA-1_371f564b92f7cf50fc2db72374e29171 |
---|---|
oai_identifier_str |
oai:scielo:S0102-695X2015000600627 |
network_acronym_str |
SBFGNOSIA-1 |
network_name_str |
Revista Brasileira de Farmacognosia (Online) |
repository_id_str |
|
spelling |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compoundsPhaeophyceaeDictyotalesMeroterpenoidsPCABiodiversitySeaweedAbstract Intraspecific variation on meroditerpenoids production by the brown marine alga Stypopodium zonale at four different populations along the Brazilian coast was analyzed using Principal Component Analysis over high-performance liquid chromatography profiles from algae extracts. The ordination of the samples by the similarities of their chromatographic traits showed the existence of three chemotypes: (i) the populations Búzios and Abrolhos which were characterized by the presence of atomaric acid (1), (ii) the population Atol das Rocas which contained the compound stypoldione (2), and (iii) the population Marataízes which was characterized by other peaks that guided the isolation of three new meroditerpenoids stypofuranlactone (3), 10,18-dihydroxy-5′a-desmethyl-5′-acetylatomaric acid (4), and the 10-keto-10-deisopropyliden-5′a-desmethyl-5′-acetylatomaric acid (5) together with the known compound the 10-keto-10-deisopropyliden-atomaric acid (6). The structures and relative stereochemistry of 3, 4 and 5 were elucidated by NMR and MS techniques. The observed chemical differences among populations of S. zonale can be related to its geographic distribution and can open an avenue to the discovery of new compounds in algae.Sociedade Brasileira de Farmacognosia2015-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600627Revista Brasileira de Farmacognosia v.25 n.6 2015reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2015.09.006info:eu-repo/semantics/openAccessSoares,Angelica R.Duarte,Heitor M.Tinnoco,Luzineide W.Pereira,Renato C.Teixeira,Valéria L.eng2015-12-22T00:00:00Zoai:scielo:S0102-695X2015000600627Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2015-12-22T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
title |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
spellingShingle |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds Soares,Angelica R. Phaeophyceae Dictyotales Meroterpenoids PCA Biodiversity Seaweed |
title_short |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
title_full |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
title_fullStr |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
title_full_unstemmed |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
title_sort |
Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds |
author |
Soares,Angelica R. |
author_facet |
Soares,Angelica R. Duarte,Heitor M. Tinnoco,Luzineide W. Pereira,Renato C. Teixeira,Valéria L. |
author_role |
author |
author2 |
Duarte,Heitor M. Tinnoco,Luzineide W. Pereira,Renato C. Teixeira,Valéria L. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Soares,Angelica R. Duarte,Heitor M. Tinnoco,Luzineide W. Pereira,Renato C. Teixeira,Valéria L. |
dc.subject.por.fl_str_mv |
Phaeophyceae Dictyotales Meroterpenoids PCA Biodiversity Seaweed |
topic |
Phaeophyceae Dictyotales Meroterpenoids PCA Biodiversity Seaweed |
description |
Abstract Intraspecific variation on meroditerpenoids production by the brown marine alga Stypopodium zonale at four different populations along the Brazilian coast was analyzed using Principal Component Analysis over high-performance liquid chromatography profiles from algae extracts. The ordination of the samples by the similarities of their chromatographic traits showed the existence of three chemotypes: (i) the populations Búzios and Abrolhos which were characterized by the presence of atomaric acid (1), (ii) the population Atol das Rocas which contained the compound stypoldione (2), and (iii) the population Marataízes which was characterized by other peaks that guided the isolation of three new meroditerpenoids stypofuranlactone (3), 10,18-dihydroxy-5′a-desmethyl-5′-acetylatomaric acid (4), and the 10-keto-10-deisopropyliden-5′a-desmethyl-5′-acetylatomaric acid (5) together with the known compound the 10-keto-10-deisopropyliden-atomaric acid (6). The structures and relative stereochemistry of 3, 4 and 5 were elucidated by NMR and MS techniques. The observed chemical differences among populations of S. zonale can be related to its geographic distribution and can open an avenue to the discovery of new compounds in algae. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600627 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000600627 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjp.2015.09.006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.25 n.6 2015 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122469645287424 |