Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae)
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2006000300002 |
Resumo: | Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Chrozophora tinctoria (Euphorbiaceae) yielded five flavonoid glycosides, quercetin 3-O-rutinoside (1, rutin), acacetin 7-O-rutinoside (2), apigenin 7-O-b-D-[(6-p-coumaroyl)]-glucopyranoside (3), apigenin 7-O- b-D-glucopyranoside (4) and apigenin 7-O-b-D-[6-(3,4-dihydroxybenzoyl)]-glucopyranoside (named, chrozophorin, 5), the last one being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques. The free-radical scavenging activity of the methanol extract (RC50 = 2.24 x 10-1 mg/mL) as well as the isolated compounds (1-5) (RC50 = 4.38 x 10-3, 2.26 x 10-2, 7.69 x 10-4, 8.71 x 10-3 and 3.19 x 10-4 mg/mL, respectively) were assessed by the DPPH assay. |
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Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae)Chrozophora tinctoriaEuphorbiaceaeflavonoidflavoneglycosidequercetinapigeninrutinchrozophorinDPPHPreparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Chrozophora tinctoria (Euphorbiaceae) yielded five flavonoid glycosides, quercetin 3-O-rutinoside (1, rutin), acacetin 7-O-rutinoside (2), apigenin 7-O-b-D-[(6-p-coumaroyl)]-glucopyranoside (3), apigenin 7-O- b-D-glucopyranoside (4) and apigenin 7-O-b-D-[6-(3,4-dihydroxybenzoyl)]-glucopyranoside (named, chrozophorin, 5), the last one being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques. The free-radical scavenging activity of the methanol extract (RC50 = 2.24 x 10-1 mg/mL) as well as the isolated compounds (1-5) (RC50 = 4.38 x 10-3, 2.26 x 10-2, 7.69 x 10-4, 8.71 x 10-3 and 3.19 x 10-4 mg/mL, respectively) were assessed by the DPPH assay.Sociedade Brasileira de Farmacognosia2006-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2006000300002Revista Brasileira de Farmacognosia v.16 n.3 2006reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2006000300002info:eu-repo/semantics/openAccessDelazar,A.Talischi,B.Nazemiyeh,H.Rezazadeh,H.Nahar,L.Sarker,S.D.eng2008-01-28T00:00:00Zoai:scielo:S0102-695X2006000300002Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2008-01-28T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
title |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
spellingShingle |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) Delazar,A. Chrozophora tinctoria Euphorbiaceae flavonoid flavone glycoside quercetin apigenin rutin chrozophorin DPPH |
title_short |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
title_full |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
title_fullStr |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
title_full_unstemmed |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
title_sort |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) |
author |
Delazar,A. |
author_facet |
Delazar,A. Talischi,B. Nazemiyeh,H. Rezazadeh,H. Nahar,L. Sarker,S.D. |
author_role |
author |
author2 |
Talischi,B. Nazemiyeh,H. Rezazadeh,H. Nahar,L. Sarker,S.D. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Delazar,A. Talischi,B. Nazemiyeh,H. Rezazadeh,H. Nahar,L. Sarker,S.D. |
dc.subject.por.fl_str_mv |
Chrozophora tinctoria Euphorbiaceae flavonoid flavone glycoside quercetin apigenin rutin chrozophorin DPPH |
topic |
Chrozophora tinctoria Euphorbiaceae flavonoid flavone glycoside quercetin apigenin rutin chrozophorin DPPH |
description |
Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Chrozophora tinctoria (Euphorbiaceae) yielded five flavonoid glycosides, quercetin 3-O-rutinoside (1, rutin), acacetin 7-O-rutinoside (2), apigenin 7-O-b-D-[(6-p-coumaroyl)]-glucopyranoside (3), apigenin 7-O- b-D-glucopyranoside (4) and apigenin 7-O-b-D-[6-(3,4-dihydroxybenzoyl)]-glucopyranoside (named, chrozophorin, 5), the last one being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques. The free-radical scavenging activity of the methanol extract (RC50 = 2.24 x 10-1 mg/mL) as well as the isolated compounds (1-5) (RC50 = 4.38 x 10-3, 2.26 x 10-2, 7.69 x 10-4, 8.71 x 10-3 and 3.19 x 10-4 mg/mL, respectively) were assessed by the DPPH assay. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2006000300002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2006000300002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2006000300002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.16 n.3 2006 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122462149017600 |