Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities

Detalhes bibliográficos
Autor(a) principal: Barbosa,Wagner Luiz Ramos
Data de Publicação: 2008
Outros Autores: Pinto,Lucianna do Nascimento, Quignard,Etienne, Vieira,José Maria dos Santos, Silva Jr.,José Otávio Carrera, Albuquerque,Sérgio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000400008
Resumo: Arrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.
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spelling Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activitiesArrabidaea chicaBignoniaceaeFlavonoidsTrichophyton mentagrophytesAntifungal activityTrypanosoma cruziTrypanocidal effectArrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.Sociedade Brasileira de Farmacognosia2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000400008Revista Brasileira de Farmacognosia v.18 n.4 2008reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2008000400008info:eu-repo/semantics/openAccessBarbosa,Wagner Luiz RamosPinto,Lucianna do NascimentoQuignard,EtienneVieira,José Maria dos SantosSilva Jr.,José Otávio CarreraAlbuquerque,Sérgioeng2009-02-18T00:00:00Zoai:scielo:S0102-695X2008000400008Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2009-02-18T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
title Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
spellingShingle Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
Barbosa,Wagner Luiz Ramos
Arrabidaea chica
Bignoniaceae
Flavonoids
Trichophyton mentagrophytes
Antifungal activity
Trypanosoma cruzi
Trypanocidal effect
title_short Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
title_full Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
title_fullStr Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
title_full_unstemmed Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
title_sort Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities
author Barbosa,Wagner Luiz Ramos
author_facet Barbosa,Wagner Luiz Ramos
Pinto,Lucianna do Nascimento
Quignard,Etienne
Vieira,José Maria dos Santos
Silva Jr.,José Otávio Carrera
Albuquerque,Sérgio
author_role author
author2 Pinto,Lucianna do Nascimento
Quignard,Etienne
Vieira,José Maria dos Santos
Silva Jr.,José Otávio Carrera
Albuquerque,Sérgio
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Barbosa,Wagner Luiz Ramos
Pinto,Lucianna do Nascimento
Quignard,Etienne
Vieira,José Maria dos Santos
Silva Jr.,José Otávio Carrera
Albuquerque,Sérgio
dc.subject.por.fl_str_mv Arrabidaea chica
Bignoniaceae
Flavonoids
Trichophyton mentagrophytes
Antifungal activity
Trypanosoma cruzi
Trypanocidal effect
topic Arrabidaea chica
Bignoniaceae
Flavonoids
Trichophyton mentagrophytes
Antifungal activity
Trypanosoma cruzi
Trypanocidal effect
description Arrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000400008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000400008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2008000400008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.18 n.4 2008
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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