Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200009 |
Resumo: | The essential oils of fresh and dried leaves and fine stems of Hyptis crenata furnished the following yields: 1.4% and 0.9%. The main volatile constituents were ±-pinene (22.0%; 19.5%), 1,8-cineole (17.6%; 23.2%), ²-pinene (17.0%; 13.8%), camphor (4.7%; 11.6%), limonene (5.4%; 4.4%) and ³-terpinene (3.5%; 2.4%), totalizing more than 70% in the oils. The DPPH radical scavenging activity (EC50, 16.7 + 0.4 µg/mL) of the methanol extract was comparable to BHT (19.8 ± 0.5 µg/mL) showing a significant antioxidant activity. The oils showed low activities. The amount of total phenolics (TP, 373.0 + 15.9 mg GAE/g) and trolox equivalent (TEAC, 226.8 + 0.5 mg TE/g) confirmed the antioxidant activity of the methanol extract that can be attributed to the presence of polar phenolic compounds. In the brine shrimp bioassay the lethal concentrations (LC50) for the oil and methanol extract were 6.7 + 0.2 µg/mL and 13.0 + 3.7 µg/mL, respectively, providing important evidence of their biological activities. |
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Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex BenthHyptis crenataLamiaceaesalva-do-marajóessential oilantioxidant activitytotal phenolic contentcytotoxicityThe essential oils of fresh and dried leaves and fine stems of Hyptis crenata furnished the following yields: 1.4% and 0.9%. The main volatile constituents were ±-pinene (22.0%; 19.5%), 1,8-cineole (17.6%; 23.2%), ²-pinene (17.0%; 13.8%), camphor (4.7%; 11.6%), limonene (5.4%; 4.4%) and ³-terpinene (3.5%; 2.4%), totalizing more than 70% in the oils. The DPPH radical scavenging activity (EC50, 16.7 + 0.4 µg/mL) of the methanol extract was comparable to BHT (19.8 ± 0.5 µg/mL) showing a significant antioxidant activity. The oils showed low activities. The amount of total phenolics (TP, 373.0 + 15.9 mg GAE/g) and trolox equivalent (TEAC, 226.8 + 0.5 mg TE/g) confirmed the antioxidant activity of the methanol extract that can be attributed to the presence of polar phenolic compounds. In the brine shrimp bioassay the lethal concentrations (LC50) for the oil and methanol extract were 6.7 + 0.2 µg/mL and 13.0 + 3.7 µg/mL, respectively, providing important evidence of their biological activities.Sociedade Brasileira de Farmacognosia2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200009Revista Brasileira de Farmacognosia v.19 n.1b 2009reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2009000200009info:eu-repo/semantics/openAccessRebelo,Monaliza M.Silva,Joyce Kelly R. daAndrade,Eloísa Helena A.Maia,José Guilherme S.eng2009-08-18T00:00:00Zoai:scielo:S0102-695X2009000200009Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2009-08-18T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
title |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
spellingShingle |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth Rebelo,Monaliza M. Hyptis crenata Lamiaceae salva-do-marajó essential oil antioxidant activity total phenolic content cytotoxicity |
title_short |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
title_full |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
title_fullStr |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
title_full_unstemmed |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
title_sort |
Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth |
author |
Rebelo,Monaliza M. |
author_facet |
Rebelo,Monaliza M. Silva,Joyce Kelly R. da Andrade,Eloísa Helena A. Maia,José Guilherme S. |
author_role |
author |
author2 |
Silva,Joyce Kelly R. da Andrade,Eloísa Helena A. Maia,José Guilherme S. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Rebelo,Monaliza M. Silva,Joyce Kelly R. da Andrade,Eloísa Helena A. Maia,José Guilherme S. |
dc.subject.por.fl_str_mv |
Hyptis crenata Lamiaceae salva-do-marajó essential oil antioxidant activity total phenolic content cytotoxicity |
topic |
Hyptis crenata Lamiaceae salva-do-marajó essential oil antioxidant activity total phenolic content cytotoxicity |
description |
The essential oils of fresh and dried leaves and fine stems of Hyptis crenata furnished the following yields: 1.4% and 0.9%. The main volatile constituents were ±-pinene (22.0%; 19.5%), 1,8-cineole (17.6%; 23.2%), ²-pinene (17.0%; 13.8%), camphor (4.7%; 11.6%), limonene (5.4%; 4.4%) and ³-terpinene (3.5%; 2.4%), totalizing more than 70% in the oils. The DPPH radical scavenging activity (EC50, 16.7 + 0.4 µg/mL) of the methanol extract was comparable to BHT (19.8 ± 0.5 µg/mL) showing a significant antioxidant activity. The oils showed low activities. The amount of total phenolics (TP, 373.0 + 15.9 mg GAE/g) and trolox equivalent (TEAC, 226.8 + 0.5 mg TE/g) confirmed the antioxidant activity of the methanol extract that can be attributed to the presence of polar phenolic compounds. In the brine shrimp bioassay the lethal concentrations (LC50) for the oil and methanol extract were 6.7 + 0.2 µg/mL and 13.0 + 3.7 µg/mL, respectively, providing important evidence of their biological activities. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200009 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200009 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2009000200009 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.19 n.1b 2009 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122463432474624 |