In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants

Detalhes bibliográficos
Autor(a) principal: Pavan,Fernando R.
Data de Publicação: 2009
Outros Autores: Sato,Daisy N., Higuchi,Célio T., Santos,Adolfo C. B., Vilegas,Wagner, Leite,Clarice Q. E
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200004
Resumo: The aim of this work was to carry out a screening of some plants of this Brazilian region with activity against Mycobacterium tuberculosis. Chloroform and methanol extracts of 37 plant species distributed among 17 families from Brazilian "Cerrado" which were tested against M. tuberculosis H37Rv and the Minimum Inhibitory Concentration (MIC) was determined by the use of Microplate Alamar Blue Assay (MABA). Crude extracts from sixteen plants showed MIC value of < 125 µg/mL and three 31.2 µg/mL. These results suggest that the Brazilian "Cerrado" may be a source of plants that have activity anti-M. tuberculosis constituents that can be extracted by polars and apolars solvents.
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spelling In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plantsBrazilian "Cerrado" plantsMycobacterium tuberculosisantitubercular activityMABAThe aim of this work was to carry out a screening of some plants of this Brazilian region with activity against Mycobacterium tuberculosis. Chloroform and methanol extracts of 37 plant species distributed among 17 families from Brazilian "Cerrado" which were tested against M. tuberculosis H37Rv and the Minimum Inhibitory Concentration (MIC) was determined by the use of Microplate Alamar Blue Assay (MABA). Crude extracts from sixteen plants showed MIC value of < 125 µg/mL and three 31.2 µg/mL. These results suggest that the Brazilian "Cerrado" may be a source of plants that have activity anti-M. tuberculosis constituents that can be extracted by polars and apolars solvents.Sociedade Brasileira de Farmacognosia2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200004Revista Brasileira de Farmacognosia v.19 n.1b 2009reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2009000200004info:eu-repo/semantics/openAccessPavan,Fernando R.Sato,Daisy N.Higuchi,Célio T.Santos,Adolfo C. B.Vilegas,WagnerLeite,Clarice Q. Eeng2009-08-18T00:00:00Zoai:scielo:S0102-695X2009000200004Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2009-08-18T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
title In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
spellingShingle In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
Pavan,Fernando R.
Brazilian "Cerrado" plants
Mycobacterium tuberculosis
antitubercular activity
MABA
title_short In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
title_full In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
title_fullStr In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
title_full_unstemmed In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
title_sort In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants
author Pavan,Fernando R.
author_facet Pavan,Fernando R.
Sato,Daisy N.
Higuchi,Célio T.
Santos,Adolfo C. B.
Vilegas,Wagner
Leite,Clarice Q. E
author_role author
author2 Sato,Daisy N.
Higuchi,Célio T.
Santos,Adolfo C. B.
Vilegas,Wagner
Leite,Clarice Q. E
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pavan,Fernando R.
Sato,Daisy N.
Higuchi,Célio T.
Santos,Adolfo C. B.
Vilegas,Wagner
Leite,Clarice Q. E
dc.subject.por.fl_str_mv Brazilian "Cerrado" plants
Mycobacterium tuberculosis
antitubercular activity
MABA
topic Brazilian "Cerrado" plants
Mycobacterium tuberculosis
antitubercular activity
MABA
description The aim of this work was to carry out a screening of some plants of this Brazilian region with activity against Mycobacterium tuberculosis. Chloroform and methanol extracts of 37 plant species distributed among 17 families from Brazilian "Cerrado" which were tested against M. tuberculosis H37Rv and the Minimum Inhibitory Concentration (MIC) was determined by the use of Microplate Alamar Blue Assay (MABA). Crude extracts from sixteen plants showed MIC value of < 125 µg/mL and three 31.2 µg/mL. These results suggest that the Brazilian "Cerrado" may be a source of plants that have activity anti-M. tuberculosis constituents that can be extracted by polars and apolars solvents.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000200004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2009000200004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.19 n.1b 2009
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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