Metabolic and biological prospecting of Coreopsis tinctoria

Detalhes bibliográficos
Autor(a) principal: Gaspar,Luís
Data de Publicação: 2012
Outros Autores: Oliveira,Andreia P., Silva,Luís R., Andrade,Paula B., Pinho,Paula Guedes de, Botelho,João, Valentão,Patrícia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200015
Resumo: Coreopsis tinctoria Nutt., Asteraceae, flowering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the first time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the main compounds. The antioxidant and antibacterial potential of this matrix was checked for the first time by several in vitro assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Antibacterial capacity was assessed against Gram-positive and Gram-negative bacteria, being more effective against the first. Additionally, acetylcholinesterase and butyrylcholinesterase inhibitory activity was also evaluated, but no effect was found. Our results provide evidence of a wide diversity of compounds with several biological properties, improving the knowledge on this poorly studied matrix, which can lead to an increment of the use of C. tinctoria flowering tops, namely in food and pharmaceutical applications.
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spelling Metabolic and biological prospecting of Coreopsis tinctoriaantibacterialantioxidantCoreopsis tinctoriafatty acidsvolatile compoundsCoreopsis tinctoria Nutt., Asteraceae, flowering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the first time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the main compounds. The antioxidant and antibacterial potential of this matrix was checked for the first time by several in vitro assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Antibacterial capacity was assessed against Gram-positive and Gram-negative bacteria, being more effective against the first. Additionally, acetylcholinesterase and butyrylcholinesterase inhibitory activity was also evaluated, but no effect was found. Our results provide evidence of a wide diversity of compounds with several biological properties, improving the knowledge on this poorly studied matrix, which can lead to an increment of the use of C. tinctoria flowering tops, namely in food and pharmaceutical applications.Sociedade Brasileira de Farmacognosia2012-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200015Revista Brasileira de Farmacognosia v.22 n.2 2012reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000224info:eu-repo/semantics/openAccessGaspar,LuísOliveira,Andreia P.Silva,Luís R.Andrade,Paula B.Pinho,Paula Guedes deBotelho,JoãoValentão,Patríciaeng2012-05-08T00:00:00Zoai:scielo:S0102-695X2012000200015Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2012-05-08T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Metabolic and biological prospecting of Coreopsis tinctoria
title Metabolic and biological prospecting of Coreopsis tinctoria
spellingShingle Metabolic and biological prospecting of Coreopsis tinctoria
Gaspar,Luís
antibacterial
antioxidant
Coreopsis tinctoria
fatty acids
volatile compounds
title_short Metabolic and biological prospecting of Coreopsis tinctoria
title_full Metabolic and biological prospecting of Coreopsis tinctoria
title_fullStr Metabolic and biological prospecting of Coreopsis tinctoria
title_full_unstemmed Metabolic and biological prospecting of Coreopsis tinctoria
title_sort Metabolic and biological prospecting of Coreopsis tinctoria
author Gaspar,Luís
author_facet Gaspar,Luís
Oliveira,Andreia P.
Silva,Luís R.
Andrade,Paula B.
Pinho,Paula Guedes de
Botelho,João
Valentão,Patrícia
author_role author
author2 Oliveira,Andreia P.
Silva,Luís R.
Andrade,Paula B.
Pinho,Paula Guedes de
Botelho,João
Valentão,Patrícia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gaspar,Luís
Oliveira,Andreia P.
Silva,Luís R.
Andrade,Paula B.
Pinho,Paula Guedes de
Botelho,João
Valentão,Patrícia
dc.subject.por.fl_str_mv antibacterial
antioxidant
Coreopsis tinctoria
fatty acids
volatile compounds
topic antibacterial
antioxidant
Coreopsis tinctoria
fatty acids
volatile compounds
description Coreopsis tinctoria Nutt., Asteraceae, flowering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the first time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the main compounds. The antioxidant and antibacterial potential of this matrix was checked for the first time by several in vitro assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Antibacterial capacity was assessed against Gram-positive and Gram-negative bacteria, being more effective against the first. Additionally, acetylcholinesterase and butyrylcholinesterase inhibitory activity was also evaluated, but no effect was found. Our results provide evidence of a wide diversity of compounds with several biological properties, improving the knowledge on this poorly studied matrix, which can lead to an increment of the use of C. tinctoria flowering tops, namely in food and pharmaceutical applications.
publishDate 2012
dc.date.none.fl_str_mv 2012-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000200015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000224
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.22 n.2 2012
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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