Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits

Detalhes bibliográficos
Autor(a) principal: Ferreira,Maria Goretty P. R.
Data de Publicação: 2010
Outros Autores: Kayano,Anderson M., Silva-Jardim,Izaltina, Silva,Tatiany O. da, Zuliani,Juliana P., Facundo,Valdir A., Calderon,Leonardo de A., Almeida-e-Silva,Alexandre de, Ciancaglini,Pietro, Stábeli,Rodrigo G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000600029
Resumo: Leishmanicidal activity of the 3-(3,4,5-trimethoxyphenyl) propanoic acid (TMPP) isolated from EtOH extracts of the Amazonian Piper turbeculatum Jacq. fruits was evaluated in vitro using Leishmania amazonensis promastigotes. The TMPP was assayed at concentrations of 1600 to 6.25 µg/mL for 24, 48, 72 and 96 h. Promastigotes viability was analyzed and the IC50 of TMPP was 145 µg/mL.
id SBFGNOSIA-1_c3cc318ac4675de2feddfa123e015887
oai_identifier_str oai:scielo:S0102-695X2010000600029
network_acronym_str SBFGNOSIA-1
network_name_str Revista Brasileira de Farmacognosia (Online)
repository_id_str
spelling Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruitsPiper tuberculatumPiperaceae3-(3,4,5-trimethoxyphenyl) propanoic acidLeishmania amazonensisleishmanicidal activityLeishmanicidal activity of the 3-(3,4,5-trimethoxyphenyl) propanoic acid (TMPP) isolated from EtOH extracts of the Amazonian Piper turbeculatum Jacq. fruits was evaluated in vitro using Leishmania amazonensis promastigotes. The TMPP was assayed at concentrations of 1600 to 6.25 µg/mL for 24, 48, 72 and 96 h. Promastigotes viability was analyzed and the IC50 of TMPP was 145 µg/mL.Sociedade Brasileira de Farmacognosia2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000600029Revista Brasileira de Farmacognosia v.20 n.6 2010reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2010005000033info:eu-repo/semantics/openAccessFerreira,Maria Goretty P. R.Kayano,Anderson M.Silva-Jardim,IzaltinaSilva,Tatiany O. daZuliani,Juliana P.Facundo,Valdir A.Calderon,Leonardo de A.Almeida-e-Silva,Alexandre deCiancaglini,PietroStábeli,Rodrigo G.eng2011-01-18T00:00:00Zoai:scielo:S0102-695X2010000600029Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-01-18T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
title Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
spellingShingle Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
Ferreira,Maria Goretty P. R.
Piper tuberculatum
Piperaceae
3-(3,4,5-trimethoxyphenyl) propanoic acid
Leishmania amazonensis
leishmanicidal activity
title_short Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
title_full Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
title_fullStr Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
title_full_unstemmed Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
title_sort Antileishmanial activity of 3-(3,4,5-trimethoxyphenyl) propanoic acid purified from Amazonian Piper tuberculatum Jacq., Piperaceae, fruits
author Ferreira,Maria Goretty P. R.
author_facet Ferreira,Maria Goretty P. R.
Kayano,Anderson M.
Silva-Jardim,Izaltina
Silva,Tatiany O. da
Zuliani,Juliana P.
Facundo,Valdir A.
Calderon,Leonardo de A.
Almeida-e-Silva,Alexandre de
Ciancaglini,Pietro
Stábeli,Rodrigo G.
author_role author
author2 Kayano,Anderson M.
Silva-Jardim,Izaltina
Silva,Tatiany O. da
Zuliani,Juliana P.
Facundo,Valdir A.
Calderon,Leonardo de A.
Almeida-e-Silva,Alexandre de
Ciancaglini,Pietro
Stábeli,Rodrigo G.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ferreira,Maria Goretty P. R.
Kayano,Anderson M.
Silva-Jardim,Izaltina
Silva,Tatiany O. da
Zuliani,Juliana P.
Facundo,Valdir A.
Calderon,Leonardo de A.
Almeida-e-Silva,Alexandre de
Ciancaglini,Pietro
Stábeli,Rodrigo G.
dc.subject.por.fl_str_mv Piper tuberculatum
Piperaceae
3-(3,4,5-trimethoxyphenyl) propanoic acid
Leishmania amazonensis
leishmanicidal activity
topic Piper tuberculatum
Piperaceae
3-(3,4,5-trimethoxyphenyl) propanoic acid
Leishmania amazonensis
leishmanicidal activity
description Leishmanicidal activity of the 3-(3,4,5-trimethoxyphenyl) propanoic acid (TMPP) isolated from EtOH extracts of the Amazonian Piper turbeculatum Jacq. fruits was evaluated in vitro using Leishmania amazonensis promastigotes. The TMPP was assayed at concentrations of 1600 to 6.25 µg/mL for 24, 48, 72 and 96 h. Promastigotes viability was analyzed and the IC50 of TMPP was 145 µg/mL.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000600029
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2010000600029
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2010005000033
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.20 n.6 2010
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
_version_ 1752122464712785920

Registros relacionados