Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract

Detalhes bibliográficos
Autor(a) principal: Gorzalczany,Susana
Data de Publicação: 2008
Outros Autores: Sülsen,Valeria, Redko,Flavia, Vescina,Cristina, Muschietti,Liliana, Martino,Virginia, Acevedo,Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100005
Resumo: The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.
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spelling Choleretic and antispasmodic effects of Lippia integrifolia aqueous extractLippia integrifoliaVerbenaceaecholeretic effectantispasmodic effectThe aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.Sociedade Brasileira de Farmacognosia2008-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100005Revista Brasileira de Farmacognosia v.18 n.1 2008reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2008000100005info:eu-repo/semantics/openAccessGorzalczany,SusanaSülsen,ValeriaRedko,FlaviaVescina,CristinaMuschietti,LilianaMartino,VirginiaAcevedo,Cristinaeng2008-04-15T00:00:00Zoai:scielo:S0102-695X2008000100005Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2008-04-15T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
title Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
spellingShingle Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
Gorzalczany,Susana
Lippia integrifolia
Verbenaceae
choleretic effect
antispasmodic effect
title_short Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
title_full Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
title_fullStr Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
title_full_unstemmed Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
title_sort Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
author Gorzalczany,Susana
author_facet Gorzalczany,Susana
Sülsen,Valeria
Redko,Flavia
Vescina,Cristina
Muschietti,Liliana
Martino,Virginia
Acevedo,Cristina
author_role author
author2 Sülsen,Valeria
Redko,Flavia
Vescina,Cristina
Muschietti,Liliana
Martino,Virginia
Acevedo,Cristina
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gorzalczany,Susana
Sülsen,Valeria
Redko,Flavia
Vescina,Cristina
Muschietti,Liliana
Martino,Virginia
Acevedo,Cristina
dc.subject.por.fl_str_mv Lippia integrifolia
Verbenaceae
choleretic effect
antispasmodic effect
topic Lippia integrifolia
Verbenaceae
choleretic effect
antispasmodic effect
description The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2008000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.18 n.1 2008
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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